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Interpretation of Endothelial Structure Related to Tumor and Atherosclerotic Blood Vessels

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Scanning Electron Microscopy of Vascular Casts: Methods and Applications

Part of the book series: Electron Microscopy in Biology and Medicine ((EMBM,volume 10))

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Abstract

Scanning electron microscopy (SEM) of vascular corrosion casts provides an opportunity to gain specific information about the luminal cellular lining of blood conduits. In addition to observation of the pattern, distribution, and density of this cellular layer, more subtle changes may be detectable. However, the determination of any of this information requires appropriate preparative procedures for highlighting the features being evaluated. For the purposes of this chapter, the discussion is primarily limited to the cellular lining of blood vessels, the vascular endothelium, and the alterations that are associated with experimental tumors and atherosclerosis. It is then possible to use the proper interpretation of endothelial surface structure to comment on the disease process itself.

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Authors and Affiliations

  1. Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, 1601 Parkview Avenue, Rockford, IL, 61107, USA

    Dr. James G. Walmsley Ph.D.

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  1. Dr. James G. Walmsley Ph.D.
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Editors and Affiliations

  1. Department of Human Anatomy, Faculty of Medicine, University of Rome “La Sapienza”, Rome, Italy

    Pietro M. Motta M.D., Ph.D.

  2. Department of Anatomy, Okayama University School of Medicine, Okayama, Japan

    Takuro Murakami M.D., Ph.D.

  3. Department of Anatomy, Osaka University Medical School, Osaka, Japan

    Hisao Fujita M.D., Ph.D.

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Walmsley, J.G. (1992). Interpretation of Endothelial Structure Related to Tumor and Atherosclerotic Blood Vessels. In: Motta, P.M., Murakami, T., Fujita, H. (eds) Scanning Electron Microscopy of Vascular Casts: Methods and Applications. Electron Microscopy in Biology and Medicine, vol 10. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3488-4_26

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  • DOI: https://doi.org/10.1007/978-1-4615-3488-4_26

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