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Autoregulation of the Heat-Shock Response

  • Chapter
Translational Regulation of Gene Expression 2

Abstract

The heat-shock proteins (hsps) were initially defined as a small set of proteins that are rapidly and dramatically induced when cells or whole organisms are exposed to high temperatures1–5 (see Fig. 1). The same proteins are induced by a wide variety of other types of stress—ethanol, heavy metal ions, and anoxia being among the most common inducing agents.

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  1. Howard Hughes Medical Institute and Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois, 60637, USA

    Susan Lindquist

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  1. Institute of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, 44106, USA

    Joseph Ilan

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Lindquist, S. (1993). Autoregulation of the Heat-Shock Response. In: Ilan, J. (eds) Translational Regulation of Gene Expression 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2894-4_14

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