Abstract
Apart from its role in flushing out debris or noxious substances from the conjunctival sac there are two practical reasons why we can be interested in the circulation of the tear fluid over the surface of the conjunctiva beneath the eyelids. The first is that after topical instillation of a drug it could be trapped in a reservoir formed by the fornices of the conjunctiva and this would control its contact time with the eye. The second is that poor mixing of the tear fluid might introduce sampling errors into the estimation of tear flow by the fluorescein dilution method1.
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References
S. Mishima, A. Gasset, S. Klyce, and J. Baum, Determination of tear volume and tear flow, Invest. Ophthalmol. 5:264 (1966).
F.T. Fraunfelder, Extraocular fluid dynamics: hour best to apply topical ocular medication, Tr. Amer. Ophthalmol. Soc. 74:457 (1976).
D.M. Maurice and S.P. Srinivas, The use of fluorometry in assessing the efficacy of cation sensitive gel as an ophthalmic vehicle: comparison with scintigraphy. J. Pharm. Sci., 81:615 (1992).
E. A. Macdonald, and D.M. Maurice, The kinetics of tear fluid under the lower lid, Exp. Eye Res. 53:421
N.M. Sang, and D.M. Maurice, Poor mixing of microdrops with the tear fluid reduces the accuracy of tear flow estimates by fluorometry, Submitted, Exp. Eye Res. (1993).
D.M. Maurice, The dynamics and drainage of tears. Int. Ophthalmol. Clin. 13:103 (1973).
M.G. Doane, Tear spreading, turnover and drainage, in: “The Prcocular Tear Film in Health, Disease and Contact Lens Wear,” F.J. Holly, ed., Dry Eye Institute, Lubock (1972).
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© 1994 Springer Science+Business Media New York
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Maurice, D.M. (1994). Mixing of the Tear Film Under the Eyelids. In: Sullivan, D.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes. Advances in Experimental Medicine and Biology, vol 350. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2417-5_44
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DOI: https://doi.org/10.1007/978-1-4615-2417-5_44
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