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The Use of DNA Polymorphisms in Genetic Mapping

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Genetic Engineering

Part of the book series: Genetic Engineering: Principles and Methods ((GEPM,volume 24))

Abstract

The introduction of molecular markers has revolutionized genetics. The range of polymorphisms that are available is increasing and the advent of large-scale cDNA and genomic sequencing is a source of an ever-increasing set of available markers. The ease with which any particular marker type can be applied to an experimental system depends, to some extent, on the amount of genomic information available for that system. However, comparative genomics is enabling a wider range of marker technology to be applied to relatively information-poor systems. The types of markers that are available include restriction fragment length polymorphisms, amplified fragment length polymorphisms, ransom amplified polymorphic DNAs, simple sequence repeats, single nucleotide polymorphisms and small insertions/deletions. The types of questions that can be addressed with these molecular markers include the generation of genetic and physical maps for the identification of interesting loci, the development of marker-based gene tags, map-based cloning of agronomically important genes, synteny mapping, marker-assisted selection and quantitative trait analysis. The continued development of technology including new high throughput methods, for example those being applied to single nucleotide polymorphisms, will change the ease with which current questions can be answered as well as enable new analyses that are presently impossible to undertake.

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References

  1. Beckman, J.S. and Soller, M. (1986) Oxford Surveys of Plant Mol. Cell. Biol. 3, 197–250.

    Google Scholar 

  2. Burrow, M.D. and Blake, T.K. (1988) 123456 in Molecular Dissection of Complex Traits (Paterson, A.H., ed.) pp. 13–29 CRC Press, Boca Raton, FL.

    Google Scholar 

  3. Gaut, B.S. and Doebley J.F. (1997) 123456 Proc. Nat. Acad. Sci. U.S.A. 94, 6808–6814.

    Article  Google Scholar 

  4. Masterson, J. (1994) 123456 Science 264, 421–424.

    Article  PubMed  CAS  Google Scholar 

  5. Powell, W., Morgante, M., Andre, C., Hanafey, M., Vogel, J., Tingey, S. and Rafalski, A.J. (1996) 123456 Mol. Breed. 2, 225–238.

    Article  CAS  Google Scholar 

  6. Williams, J.G.K., Kubelik, A.R., Livak, J., Rafalski, AJ.A., and Tingey, S.V. (1990) 123456 Nucl. Acids Res. 18, 6531–6535.

    Article  PubMed  CAS  Google Scholar 

  7. Vos, P., Hogers, R., Bleeker, M., Rijans, M., Van de Lee, T., Homes, M., Frijters, A., Pot, J., Peleman, J., Kuiper, M., and Zabeau, M. (1995) 123456 Nucl. Acids Res. 23, 4407–4414.

    Article  PubMed  CAS  Google Scholar 

  8. Senior, M.I. and Heun, M. (1993) 123456 Genome 36, 884–889.

    Article  PubMed  CAS  Google Scholar 

  9. Brenner, S. and Livak, K.J. (1989) 123456 Proc. Nat. Acad. Sci. U.S.A. 86, 8902–8906.

    Article  CAS  Google Scholar 

  10. Marra, M.A., Kucaba, T.A., Dietrich, N.L., Green, E.D., Brownstein, B., Wilson, R.K., McDonald, K.M., Hillier, L.W., McPherson, J.D. and Waterston, R.H. (1997) 123456 Genome Res. 7, 1072–1084.

    PubMed  CAS  Google Scholar 

  11. Cai, W.W., Reneker, J., Chow, C.W., Vaishnav, M. and Bradley, A. (1998) 123456 Genomics 54, 387–397.

    Article  PubMed  CAS  Google Scholar 

  12. Panaud, O., Chen, X.L., and McCouch, S.R. (1995) 123456 Genome 38, 1170–1176.

    Article  PubMed  CAS  Google Scholar 

  13. Kristensen, V.N., Kelefiotis, D., Kristensen, T. and Borresen-Dale, A. (2001) 123456 BioTechniques 30, 318–332.

    PubMed  CAS  Google Scholar 

  14. Lai, E. (2001) 123456 Genome Res. 11, 927–929.

    Article  PubMed  CAS  Google Scholar 

  15. Smith, D., Yanai, Y., Liu, Y.-G., Ishiguro, S., Okada, K., Shibata, D., Whittier, R.F. and Fedoroff, N.V. (1996) 123456 Plant J. 10, 721–732.

    Article  PubMed  CAS  Google Scholar 

  16. McCallum, C.M., Cornai, L., Greene, E.A. and Henikoff, S. (2000) 123456 Nature Biotechnol. 18, 455–457.

    Article  CAS  Google Scholar 

  17. Stuber, C.W., Polacco, M. and Senior, M.L. (1999) 123456 Crop Sci. 39, 1571–1583.

    Article  Google Scholar 

  18. Burghes, A.H.M., VaeSsin, H.E.F., and de la Chapelle, A. (2001) 123456 Science 293, 2213–2215.

    Article  PubMed  CAS  Google Scholar 

  19. Botstein, D., White, R.L., Skolnick, M. and Davis, R.W. (1980) 123456 Amer. J. Hum. Genet. 32, 314–331.

    PubMed  CAS  Google Scholar 

  20. Mba, R.E.C., Stephenson, P., Edwards, K., Melzer, S., Nkumbira, J., Gullberg, U., Appel, K., Gale, M., Tohme, J. and Fregene, M. (2001) 123456 Theoret. App. Genet. 102, 21–31.

    Article  CAS  Google Scholar 

  21. Testolin, R., Huang, W.G., Lain, O., Messina, R., Vecchione, A. and Cipriani, G. (2001) 123456 Theoret. App. Genet. 103, 30–36.

    Article  CAS  Google Scholar 

  22. Duval, M.F., Noyer, J.L., Perrier, X., d’Eeckenbrugge, G.C. and Hamon, P. (2001) 123456 Theoret. App. Genet. 102, 83–90.

    Article  CAS  Google Scholar 

  23. Visscher, P.M., Mackinnon, M. and Haley, C.S. (1997) 123456 Anim. Biotechnol. 8, 99–106.

    Article  Google Scholar 

  24. Hospital, F. (2001) 123456 Genetics 158, 1363–1379.

    PubMed  CAS  Google Scholar 

  25. Moreau, L., Lemarie, S., Charcosset, A. and Gallais, A. (2000) 123456 Crop Sci. 40, 329–337.

    Article  Google Scholar 

  26. Beuzen, N.D., Stear, M.J. and Chang, K.C. (2000) 123456 Vet. J. 160, 42–52.

    Article  PubMed  CAS  Google Scholar 

  27. Graham, G.I., Wolff, D.W. and Stuber, C.W. (1997) 123456 Crop Sci. 37, 1601–1610.

    Article  CAS  Google Scholar 

  28. Yamamoto, T., Kuboki, Y., Lin, S.Y., Sasaki, T. and Yano, M. (1998) 123456 Theoret. App. Genet. 97, 37–44.

    Article  CAS  Google Scholar 

  29. Paterson, A.H. (1988) 123456 in Molecular Dissection of Complex Traits (Paterson, A.H., ed.) pp. 289–293 CRC Press, Boca Raton, FL.

    Google Scholar 

  30. Tanksley, S.D. (1993) 123456 Annu. Rev. Genet. 27, 205–233.

    Article  PubMed  CAS  Google Scholar 

  31. Paterson, A.H., Lin, Y-R., Li, Z., Schertz, K.F., Doebley, J.F., Pinson, S.R.M., Liu, S-C., Stansel, J.W. and Irvine, J. (1995) 123456 Science 269, 1714–1718.

    Article  PubMed  CAS  Google Scholar 

  32. Heyen, D.W., Weller, J.I., Ron, M., Band, M., Beever, J.E., Feldmesser, E., Da, Y., Wiggans, G.R., VanRaden, P.M. and Lewin, H.A. (1999) 123456 Physiolog. Genom. 1, 165–175.

    CAS  Google Scholar 

  33. Schrooten, C., Bovenhuis, H., Coppieters, W. and Van Arendonk, J.A.M. (2000) 123456 J. Dairy Sci. 83, 795–806.

    Article  PubMed  CAS  Google Scholar 

  34. Frary, A., Nesbittm T.C., Frary, A., Grandillo, S., van der Knaap, E., Cong, B., Liu, J., Meller, J., Elber, R., Alpert, K.B. and Tanksley, S.D. (2000) 123456 Science 289, 85–88.

    Article  PubMed  CAS  Google Scholar 

  35. Tanksley, S.D. and McCouch, S.R. (1997) 123456 Science 277, 1063–1066.

    Article  PubMed  CAS  Google Scholar 

  36. Ohno, S. (1970) in Evolution by Gene Duplication, pp. 137–146, Springer-Verlag, New York, NY.

    Google Scholar 

  37. Helentjaris, T., Weber, D. and Wright, S. (1988) 123456 Genetics 118, 353–364.

    PubMed  CAS  Google Scholar 

  38. Blanc, G., Barakat, A., Guyot, R., Cooke, R. and Delseney, M. (2000) 123456 Plant Cell 12, 1093–1101.

    PubMed  CAS  Google Scholar 

  39. Lagercrantz, U. (1998) 123456 Genetics 150, 1217–1228.

    PubMed  CAS  Google Scholar 

  40. McCouch, S.R. (2001) 123456 Plant Physiol. 125, 152–155.

    Article  PubMed  CAS  Google Scholar 

  41. Bonierbale, M.W., Plaisted, R.L. and Tanksley, S.D. (1998) 123456 Genetics 120, 1095–1103.

    Google Scholar 

  42. Van Deynze, A.E., Sorrells, M.E., Park, W.D., Ayres, N.M., Fu, H., Cartinhour, S.W., Paul, E. and McCouch, S.R. (1998) 123456 Theor. Appl. Genet. 97, 356–369.

    Article  Google Scholar 

  43. Devos, K.M. and Gale, M.D. (1997) 123456 Plant Mol. Biol. 35, 3–15.

    Article  PubMed  CAS  Google Scholar 

  44. Bennetzen, J.L., SanMiguel, P., Chen, M., Tikhonov, A., Francki, M. and Avramova, Z. (1998) 123456 Proc. Nat. Acad. Sci. U.S.A. 95, 1975–1978.

    Article  CAS  Google Scholar 

  45. O’Neill, C.M. and Bancroft, I. (2000) 123456 Plant J. 23, 233–243.

    Article  PubMed  Google Scholar 

  46. Wilson, W.A., Harrington, S.E., Woodman, W.L., Lee, M., Sorrells, M.E. and McCouch, S.R. (1999) 123456 Genetics 153, 453–473.

    PubMed  CAS  Google Scholar 

  47. Kilian, A., Chen, J., Han, F., Steffenson, B. and Kleinhofs, A. (1997) 123456 Plant Mol. Biol. 35, 187–195.

    Article  PubMed  CAS  Google Scholar 

  48. The Arabidopsis Genome Initiative (2000) 123456 Nature 408, 796–815.

    Article  Google Scholar 

  49. Yu, J. et al. (2001) 123456 Chinese Science Bulletin 46, 1937–1942.

    Article  CAS  Google Scholar 

  50. Michelmore, R.W. and Meyers, B.C. (1998) 123456 Genome Res. 8, 1113–1130.

    PubMed  CAS  Google Scholar 

  51. Stewart, E.A. et al. (1997) 123456 Genome Res. 7, 422–433.

    PubMed  CAS  Google Scholar 

  52. Kynast, R.G., Riera-Lizarazu, O., Vales, M.I., Okagaki R.J., Maquieira, S.B., Chen, G., Ananiev, E.V., Odland, W.E., Russell, C.D., Stec, A.O., Livingston, S.M., Zaia, H.A., Rines, H.W. and Phillips, R.L. (2001) 123456 Plant Physiol. 125, 1216–1227.

    Article  PubMed  CAS  Google Scholar 

  53. Rodi, C. (2001) Advances in Genome Biology and Technology. Meeting Abstract G Corp. MA.

    Google Scholar 

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Cullis, C.A. (2002). The Use of DNA Polymorphisms in Genetic Mapping. In: Setlow, J.K. (eds) Genetic Engineering. Genetic Engineering: Principles and Methods, vol 24. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0721-5_8

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  • DOI: https://doi.org/10.1007/978-1-4615-0721-5_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5210-5

  • Online ISBN: 978-1-4615-0721-5

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