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Formation and Structure of Mammalian Ovaries

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Introduction to Mammalian Reproduction
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Abstract

It is generally accepted that the ability to reproduce is one of the most essential properties of living organisms. Various forms of life are capable of reproducing themselves from one generation to the next under appropriate conditions. Some species reproduce only once during their life span, whereas others, such as mammals, have reproductive cycles that are hormonally regulated; the female ovary is central to the process of reproduction and produces germ cells, as well as gonadal hormones.

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References

  1. Upadhyay S., Zamboni L. Ectopic germ cells: natural model for the study of germ cell sexual differentiation. Proc Natl Acad Sci USA 1982; 79:6584–6587.

    Article  PubMed  CAS  Google Scholar 

  2. Baker T.G. A quantitative and cytological study of germ cells in human ovaries. Proc Roy SocB 1963; 158:417–433.

    Article  CAS  Google Scholar 

  3. Baker T.G. A quantitative and cytological study of oogenesis in the rhesus monkey. J Anat 1966; 100: 761–776.

    PubMed  CAS  Google Scholar 

  4. Alberts B., Bray D., Lewis J., Raff M., Roberts K., Watson J.D. Germ cells and fertilization. In: Molecular Biology of the Cell (3rd ed.), New York, Garland Publishing; 1994; 1011–1035.

    Google Scholar 

  5. Yanagimachi R. Mammalian fertilization. In: Knobil E, Neill JD (eds.) The Physiology of Reproduction, vol.1. New York, Raven Press; 1994: 189–317.

    Google Scholar 

  6. Tesoriero J.V. Formation of the chorion (zona pellucida) in the teleost, Oryzias latipes. II. Polysaccharide cytochemistry of early oogenesis. J Histochem Cytochem 1977; 25: 1376–1380.

    Article  PubMed  CAS  Google Scholar 

  7. Guraya SS. Recent advances in the morphology, histochemistry, and biochemistry of the developing mammalian ovary. Int Rev Cytol 1977; 51:49–131.

    Article  PubMed  CAS  Google Scholar 

  8. Takagi J., Araki Y., Dobashi M., Imai Y., Hiroi M., Tonosaki A., Sendo F. The development of porcine zona pellucida using monoclonal antibodies: I. Immunochemistry and light microscopy. Biol Reprod 1989; 40: 1095–1102.

    Article  PubMed  CAS  Google Scholar 

  9. Takagi J., Dobashi M., Araki Y., Imai Y., Hiroi M., Tonosaki A., Sendo F. The development of porcine zona pellucida using monoclonal antibodies: II. Electron microscopy. Biol Reprod 1989; 40: 1103–1108.

    Article  PubMed  CAS  Google Scholar 

  10. Akatsuka K., Yoshida-Komiya H., Tulsiani D.R.P., Orgebin-Crist M.-C, Hiroi M., Araki Y. Rat zona pellucida glycoproteins: Molecular cloning and characterization of the three major components. Mol Reprod Dev 1998; 51: 454–467.

    Article  PubMed  CAS  Google Scholar 

  11. Haddad A., Nagai M.E. Radioautographic study of glycoprotein biosynthesis and renewal in the ovarian follicles of mice and the origin of the zona pellucida. Cell Tissue Res 1977; 177: 347–369.

    PubMed  CAS  Google Scholar 

  12. Bleil J.D., Wassarman P.M. Structure and function of the zona pellucida: identification and characterization of the proteins of the mouse oocyte’s zona pellucida. Dev Biol 1980; 76:185–202.

    Article  PubMed  CAS  Google Scholar 

  13. Greve J.M., Salzmann G.S., Roller R.J., Wassarman P.M. Biosynthesis of the major zona pellucida glycoprotein secreted by oocytes during mammalian oogenesis. Cell 1982; 31:749–759.

    Article  PubMed  CAS  Google Scholar 

  14. Zamboni L., Upadhyay S. Germ cell differentiation in mouse adrenal glands. J Exp Zool 1983;228:173–193.

    Article  PubMed  CAS  Google Scholar 

  15. Liu Y.X., Hsueh A.J. Synergism between granulosa and theca-interstitial cells in estrogen synthesis by gonadotropin-treated rat ovaries: studies on the two-cell, two-gonadotropin hypothesis using steroid antisera. Biol Reprod 1986; 35:27–36.

    Article  PubMed  CAS  Google Scholar 

  16. Hughes F.M., Gorospe W.C. Biochemical identification of apoptosis (programmed cell death) in granulosa cells: evidence for a potential mechanism underlying follicular atresia. Endocrinology 1991; 129:2415–2422.

    Article  PubMed  CAS  Google Scholar 

  17. Tilly J.L., Kowalski K.I., Johnson A.L., Hsueh A. J. Involvement of apoptosis in ovarian follicular atresia and postovulatory regression. Endocrinology 1991; 129:2799–2801.

    Article  PubMed  CAS  Google Scholar 

  18. Yonehara S., Ishii A., Yonehara M. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 1989;169:1747–1756.

    Article  PubMed  CAS  Google Scholar 

  19. Suda T., Takahashi T., Golstein P., Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993;75:1169–1178.

    Article  PubMed  CAS  Google Scholar 

  20. Guo M.W., Mori E., Xu J.P., Mori T. Identification of Fas antigen associated with apoptotic cell death in murine ovary. Biochem Biophys Res Commun 1994;203:1438–1446.

    Article  PubMed  Google Scholar 

  21. Hakuno N., Koji T., Yano T., Kobayashi N., Tsutsumi O., Taketani Y., Nakane P.K. Fas/APO-l/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia. Endocrinology 1996;137:1938–1948.

    Article  PubMed  CAS  Google Scholar 

  22. Guo M.W., Xu J.P., Mori E., Sato E., Saito S., Mori T. Expression of Fas ligand in murine ovary. Am J Reprod Immunol 1997;37:391–398.

    Article  PubMed  Google Scholar 

  23. Mori T., Xu J.P., Mori E., Sato E., Saito S., Guo M.W. Expression of Fas-Fas ligand system associated with atresia through apoptosis in murine ovary. Hormone Res 1997;48 Suppl 3:11–19.

    PubMed  Google Scholar 

  24. Xu J.P., Li X., Mori E., Sato E., Saito S., Guo M.W., Mori T. Expression of Fas-Fas ligand system associated with atresia in murine ovary. Zygote 1997; 5:321–327.

    PubMed  Google Scholar 

  25. Koering M.J., Goodman A.L., Williams R.F., Hodgen G.D. Granulosa cell pyknosis in the dominant follicle of monkeys. Fertil Steril 1982; 37:837–844.

    PubMed  CAS  Google Scholar 

  26. Carson R.S., Findlay J.K., Burger H.G., Trounson A.O. Gonadotropin receptors of the ovine ovarian follicle during follicular growth and atresia. Biol Reprod 1979; 21:75–87.

    Article  PubMed  CAS  Google Scholar 

  27. Bortolussi M., Marini G., Reolon M.L. A histochemical study of the binding of 1251-HCG to the rat ovary throughout the estrous cycle. Cell Tissue Res 1979; 197:213–226.

    Article  PubMed  CAS  Google Scholar 

  28. Uilenbroek J.T., Richards J.S. Ovarian follicular development during the rat estrous cycle: gonadotropin receptors and follicular responsiveness. Biol Reprod 1979; 20:1159–1165.

    Article  PubMed  CAS  Google Scholar 

  29. Oxberry B.A., Greenwald G.S. An autoradiographic study of the binding of 125 I-iabeled follicle-stimulating hormone, human chorionic gonadotropin and prolactin to the hamster ovary throughout the estrous cycle. Biol Reprod 1982; 27:505–516.

    Article  PubMed  CAS  Google Scholar 

  30. Bellin M.E., Ax RL. Chondroitin sulfate: an indicator of atresia in bovine follicles. Endocrinology 1984; 114:428–434.

    Article  PubMed  CAS  Google Scholar 

  31. Asselin E., Xiao C.W., Wang Y.F., Tsang B.K. Mammalian follicular development and atresia: role of apoptosis. Biol Signals Receptors. 2000; 9:87–95.

    Article  CAS  Google Scholar 

  32. Byskov A.G. Cell kinetic studies of follicular atresia in the mouse ovary. J Reprod Fertil 1974;37:277–285.

    Article  PubMed  CAS  Google Scholar 

  33. Peluso J.J., England-Charlesworth C, Bolender D.L., Steger R.W. Ultrastructural alterations associated with the initiation of follicular atresia. Cell Tissue Res 1980; 211:105–115.

    Article  PubMed  CAS  Google Scholar 

  34. Bukovsky A., Chen T.T., Wimalasena J., Caudle M.R. Cellular localization of luteinizing hormone receptor immunoreactivity in the ovaries of immature, gonadotropin-primed and normal cycling rats. Biol Reprod 1993; 48:1367–1382.

    Article  PubMed  CAS  Google Scholar 

  35. Bukovsky A., Caudle M.R., Keenan J.A., Wimalasena J., Foster J.S., Van Meter S.E. Quantitative evaluation of the cell cycle-related retinoblastoma protein and localization of Thy-1 differentiation protein and macrophages during follicular development and atresia, and in human corpora lutea. Biol Reprod 1995; 52:776–792.

    Article  PubMed  Google Scholar 

  36. Kasuya K. The process of apoptosis in follicular epithelial cells in the rabbit ovary, with special reference to involvement by macrophages. Arc Histol Cytol 1995;58:257–264.

    Article  CAS  Google Scholar 

  37. Kasuya K. Elimination of apoptotic granulosa cells by intact granulosa cells and macrophages in atretic mature follicles of the guinea pig ovary. Arc Histol Cytol 1997; 60:175–184.

    Article  CAS  Google Scholar 

  38. Koike K., Watanabe H., Hiroi M., Tonosaki A. Gap junction of stratum granulosum cells of mouse follicles: immunohistochemistry and electron microscopy. J Elect Microscopy 1993;42:94–106.

    CAS  Google Scholar 

  39. Watanabe H., Tonosaki A. Gap junction in the apoptosis: TEM observation of membrana-granulosa cells of mouse ovarian follicle. Prog Cell Res 1995; 4: 37–40.

    Google Scholar 

  40. Inoue S., Watanabe H., Saito H., Hiroi M., Tonosaki A. Elimination of atretic follicles from the mouse ovary: a TEM and immunohistochemical study in mice. J Anat 2000; 196:103–110.

    Article  PubMed  Google Scholar 

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Araki, Y. (2003). Formation and Structure of Mammalian Ovaries. In: Tulsiani, D.R.P. (eds) Introduction to Mammalian Reproduction. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0273-9_9

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  • DOI: https://doi.org/10.1007/978-1-4615-0273-9_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4998-3

  • Online ISBN: 978-1-4615-0273-9

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