Skip to main content

Movement-Related Cortical Potentials in Patients with Focal Brain Lesions

  • Chapter

Abstract

Some of the unanswered questions regarding movement-related cortical potentials (MRCPs) in general, and the Bereitschaftspotential in particular, concern their likely generators and whether these are active in parallel or sequentially. At the behavioral level, it still needs to be clarified, whether preparation, intention to act, anticipation or a combination of these contribute to the generation of different MRCP components. Alterations of MRCPs due to focal brain lesions may help to answer some of these questions.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Barrett, G., Shibasaki, H. and Neshige, R. (1986) Cortical potentials preceding voluntary movement: evidence for three periods of preparation in man. Electroencephalogr. Clin. Neurophysiol., 63, 327–39.

    Article  PubMed  CAS  Google Scholar 

  • Boetzel, K., Plendl, H., Paulus, W. and Scherg, M. (1993) Bereitschaftspotential: is there a contribution of the supplementary motor area? Electroencephalogr. Clin. Neurophysiol., 89, 187–96.

    Article  Google Scholar 

  • Chollet, F., DiPiero, V., Wise, R. J., Brooks, D. J., Dolan, R. J. and Frackowiak, R. S. (1991) The functional anatomy of motor recovery after stroke in humans: a study with positron emission tomography. Ann. Neurol., 29, 63–71.

    Article  PubMed  CAS  Google Scholar 

  • Cramer, S. C, Nelles, G., Benson, R. R., Kaplan, J. D., Parker, R. A., Kwong, K. K., Kennedy, D. N., Finklestein, S. P.and Rosen, B. R. (1997) A functional MRI study of subjects recovered from hemiparetic stroke. Stroke, 28,2518–27.

    Article  PubMed  CAS  Google Scholar 

  • Deecke, L. (1987) Bereitschaftspotential as an indicator of movement preparation in supplementary motor area and motor cortex. Ciba Found. Symp., 132, 231–50.

    PubMed  CAS  Google Scholar 

  • Deecke, L., Eisinger, H. and Kornhuber, H. H. (1980) Comparison of Bereitschaftspotential, pre-motion positivity and motor potential preceding voluntary flexion and extension movements in man. Prog. Brain Res., 54, 171–6.

    Article  PubMed  CAS  Google Scholar 

  • Deecke, L., Kornhuber, H. H., Lang, W., Lang, M. and Schreiber, H. (1985) Timing function of the frontal cortex in sequential motor and learning tasks. Hum. Neurobiol., 4, 143–54.

    PubMed  CAS  Google Scholar 

  • Deecke, L., Lang, W., Heller, H. J., Hufnagl, M. and Kornhuber, H. H. (1987) Bereitschaftspotential in patients with unilateral lesions of the supplementary motor area. J. Neurol. Neurosurg. Psychiatry, 50, 1430–4.

    Article  PubMed  CAS  Google Scholar 

  • Deiber, M. P., Ibanez, V., Sadato, N. and Hallett, M. (1996) Cerebral structures participating in motor preparation in humans - a positron emission tomography study. J. Neurophysiol., 75, 233–47.

    PubMed  CAS  Google Scholar 

  • Deiber, M. P., Passingham, R. E., Colebatch, J. G., Friston, K. J., Nixon, P. D. and Frackowiak, R. S. J. (1991) Cortical areas and the selection of movement: a study with positron emission tomography. Exp. Brain Res., 84, 393–402.

    Article  PubMed  CAS  Google Scholar 

  • Deiber, M. P., Wise, S. P., Honda, M., Catalan, M. J., Grafman, J. and Hallett, M. (1997) Frontal and parietal networks for conditional motor learning: a positron emission tomography study. J. Neurophysiol., 78, 977–91.

    PubMed  CAS  Google Scholar 

  • Erdler, M., Beisteiner, R., Mayer, D., Kaindl, T., Edward, V., Windischberger, C., Lindinger, G. and Deecke, L. (2000) Supplementary motor area activation preceding voluntary movement is detectable with a whole-scalp magnetoencephalography system. Neuroimage, 11, 697–707.

    Article  PubMed  CAS  Google Scholar 

  • Fève, A., Bathien, N. and Rondot, P. (1994) Abnormal movement related potentials in patients with lesions of basal ganglia and anterior thalamus. J. Neurol. Neurosurg. Psychiatry, 57, 100–4.

    Article  PubMed  Google Scholar 

  • Gerloff, C., Altenmüller, E. and Dichgans, J. (1996a) Disintegration and reorganization of cortical motor processing in 2 patients with cerebellar stroke. Electroencephalogr. Clin. Neurophysiol., 98, 59–68.

    Article  CAS  Google Scholar 

  • Gerloff, C., Corwell, B., Chen, R., Hallett, M. and Cohen, L. G. (1997a) Stimulation over the human supplementary motor area interferes with the organization of future elements in complex motor sequences. Brain, 120, 1587–1602.

    Article  PubMed  Google Scholar 

  • Gerloff, C., Grodd, W., Altenmüller, E., Kolb, R., Nägele, T., Klose, U., Voigt, K. and Dichgans, J. (1996b)Coregistration of EEG and fMRI in a simple motor task. Human Brain Mapping, 4, 199–209.

    Article  PubMed  CAS  Google Scholar 

  • Gerloff, C., Toro, C., Uenishi, N., Cohen, L. G., Leocani, L. and Hallett, M. (1997b) Steady-state movement-related cortical potentials: A new approach to assessing cortical activity associated with fast repetitive finger movements. Electroencephalogr. Clin. Neurophysiol., 102, 106–113.

    Article  CAS  Google Scholar 

  • Gerloff, C., Uenishi, N. and Hallett, M. (1998a) Cortical activation during fast repetitive finger movements in humans:Dipole sources of steady-state movement-related cortical potentials. J. Clin. Neurophysiol., 15, 502–13.

    Article  PubMed  CAS  Google Scholar 

  • Gerloff, C., Uenishi, N., Nagamine, T., Kunieda, T., Hallett, M. and Shibasaki, H. (1998b) Cortical activation during fast repetitive finger movements in humans: Steady-state movement-related magnetic fields and their cortical generators. Electroenceph. Clin. Neurophysiol., 109, 444–53.

    CAS  Google Scholar 

  • Green, J. B., Bialy, Y., Sora, E. and Ricamato, A. (1999) High-resolution EEG in poststroke hemiparesis can identify ipsilateral generators during motor tasks. Stroke, 30, 2659–65.

    Article  PubMed  CAS  Google Scholar 

  • Hallett, M. (1994) Movement-related cortical potentials. Electromyogr. Clin. Neurophysiol., 34, 5–13.

    PubMed  CAS  Google Scholar 

  • Hallett, M. and Toro, C. (1996) In Supplementary sensorimotor area, Vol. 70 (Ed, Lüders, H. O. ) Lippincott-Raven,Philadelphia, pp. 147–152.

    Google Scholar 

  • Hamdy, S. and Rothwell, J. C. (1998) Gut feelings about recovery after stroke: the organization and reorganization of human swallowing motor cortex. Trends Neurosci., 21, 278–82.

    Article  PubMed  CAS  Google Scholar 

  • Holmes, G. (1917) The symptoms of acute cerebellar injuries due to gunshot injuries. Brain, 40, 461–535.

    Article  Google Scholar 

  • Honda, M., Nagamine, T., Fukuyama, H., Yonekura, Y., Kimura, J. and Shibasaki, H. (1997) Movement-related cortical potentials and regional cerebral blood flow change in patients with stroke after motor recovery. J. Neurol. Sci.,146, 117–26.

    Article  PubMed  CAS  Google Scholar 

  • Ikeda, A., Lüders, H. O., Burgess, R. C. and Shibasaki, H. (1992) Movement-related potentials recorded from supplementary motor area and primary motor area. Role of supplementary motor area in voluntary movements.Brain, 95, 323–334.

    Google Scholar 

  • Ikeda, A., Shibasaki, H., Nagamine, T., Terada, K., Kaji, R., Fukuyama, H. and Kimura, J. (1994) Dissociation between contingent negative variation and Bereitschaftspotential in a patient with cerebellar efferent lesion.Electroencephalogr. Clin. Neurophysiol., 90, 359–64.

    Article  PubMed  CAS  Google Scholar 

  • Kitamura, J., Shibasaki, H. and Takeuchi, T. (1996) Cortical potentials preceding voluntary elbow movement in recovered hemiparesis. Electroencephalogr. Clin. Neurophysiol., 98, 149-56. Knight, R. T., Singh, J. and Woods, D. L. (1989) Pre-movement parietal lobe input to human sensorimotor cortex. Brain Res., 498, 190–4.

    Google Scholar 

  • Kornhuber, H. H. and Deecke, L. (1964) Hirnpotentialänderungen beim Menschen vor und nach Willkürbewegungen,dargestellt mit Magnetband-Speicherung und Rückwärtsanalyse. Pflügers Arch., 281, 52.

    Google Scholar 

  • Kornhuber, H. H. and Deecke, L. (1965) Hirnpotentialänderungen bei Willkürbewegungen und passiven Bewegungen des Menschen: Bereitschaftspotential und reafferente Potentiale. Pflügers Arch., 284, 1–17.

    Article  CAS  Google Scholar 

  • Lang, W., Cheyne, D., Kristeva, R., Beisteiner, R., Lindinger, G. and Deecke, L. (1991) Three-dimensional localization of SMA activity preceding voluntary movement. A study of electric and magnetic fields in a patient with infarction of the right supplementary motor area. Exp. Brain Res., 87, 688–95.

    Article  PubMed  CAS  Google Scholar 

  • Laplane, D., Talairach, J., Meininger, V., Bancaud, J. and Orgogozo, J. M. (1977) Clinical consequences of corticectomies involving the supplementary motor area in man. J. Neurol. Sci., 34, 301–14.

    Article  PubMed  CAS  Google Scholar 

  • Lim, S. H., Dinner, D. S., Pillay, P. K., Lüders, H., Morris, H. H., Klem, G., Wyllie, E. and Awad, I. A. (1994) Functional anatomy of the human supplementary sensorimotor area: results of extraoperative electrical stimulation.Electroencephalogr. Clin. Neurophysiol., 91, 179–93.

    Article  PubMed  CAS  Google Scholar 

  • Mackinnon, C. D., Kapur, S., Hussey, D., Verrier, M. C., Houle, S. and Tatton, W. G. (1996) Contributions of the mesial frontal-cortex to the premovement potentials associated with intermittent hand movements in humans. Human Brain Mapping, 4, 1–22.

    Article  PubMed  CAS  Google Scholar 

  • Nagamine, T., Toro, C., Balish, M., Deuschl, G., Wang, B., Sato, S., Shibasaki, H. and Hallett, M. (1994) Cortical magnetic and electric fields associated with voluntary finger movements. Brain Topogr., 6, 175–83.

    Article  PubMed  CAS  Google Scholar 

  • Netz, J., Lammers, T. and Homberg, V. (1997) Reorganization of motor output in the non-affected hemisphere after stroke. Brain, 120, 1579–86.

    Article  PubMed  Google Scholar 

  • Platz, T., Kim, I. H., Pintschovius, H., Winter, T., Kieselbach, A., Villringer, K., Kurth, R. and Mauritz, K. H. (2000) Multimodal EEG analysis in man suggests impairment-specific changes in movement-related electric brain activity after stroke. Brain, 123 Pt 12, 2475–90.

    Article  PubMed  CAS  Google Scholar 

  • Praamstra, P., Stegeman, D. F., Horstink, M. W. and Cools, A. R. (1996) Dipole source analysis suggests selective modulation of the supplementary motor area contribution to the readiness potential. Electroencephalogr. Clin.Neurophysiol., 98, 468–77.

    Article  PubMed  CAS  Google Scholar 

  • Roland, P. E. (1984) Organization of motor control by the normal human brain. Hum. Neurobiol., 2, 205–16.

    PubMed  CAS  Google Scholar 

  • Rossini, P. M., Caltagirone, C., Castriota-Scanderbeg, A., Cicinelli, P., Del Gratta, C., Demartin, M., Pizzella, V.,Traversa, R, and Romani, G. L. (1998) Hand motor cortical area reorganization in stroke: a study with fMRI,MEG and TCS maps. Neuroreport, 9, 2141–6.

    Article  PubMed  CAS  Google Scholar 

  • Saitoh, T., Kamiya, H., Mizuno, Y., Shimizu, N., Niijima, K., Ohbayashi, T. and Yoshida, M. (1987) Neurophysiological analysis of ataxia in capsular ataxic hemiparesis. J. Neurol. Sci., 79, 221–8.

    Article  PubMed  CAS  Google Scholar 

  • Sakai, K., Hikosaka, O., Miyauchi, S., Takino, R., Sasaki, Y. and Pütz, B. (1998) Transition of Brain Activation from Frontal to Parietal Areas in Visuomotor Sequence Learning. J. Neurosci., 18, 1827–40.

    PubMed  CAS  Google Scholar 

  • Sasaki, K. and Gemba, H. (1984) Compensatory motor function of the somatosensory cortex for the motor cortex temporarily impaired by cooling in the monkey. Exp. Brain Res., 55, 60–68.

    Article  PubMed  CAS  Google Scholar 

  • Sasaki, K. and Gemba, H. (1991) In Event-related brain research (EEG Suppl. 42)(Eds, Brunia, C. H. M., Mulder, G. and Verbaten, M. N. ) Elsevier, Amsterdam, pp. 80–96.

    Google Scholar 

  • Sasaki, K., Gemba, H., Hashimoto, S. and Mizuno, N. (1979) Influences of cerebellar hemispherectomy on slow potentials in the motor cortex preceding self-paced hand movements in the monkey. Neurosci. Lett., 15, 23–28.

    Article  PubMed  CAS  Google Scholar 

  • Sasaki, K., Gemba, H. and Tsujimoto, T. (1989) Suppression of visually initiated hand movement by stimulation of the prefrontal cortex in the monkey. Brain Res., 495, 100–7.

    Article  PubMed  CAS  Google Scholar 

  • Shibasaki, H. (1975) Movement-associated cortical potentials in unilateral cerebral lesions. J. Neurol., 209, 189–98.

    Article  PubMed  CAS  Google Scholar 

  • Shibasaki, H., Barrett, G., Halliday, E. and Halliday, A. M. (1980) Components of the movement-related cortical potential and their scalp topography. Electroencephalogr. Clin. Neurophysiol., 49, 213–26.

    Article  PubMed  CAS  Google Scholar 

  • Shibasaki, H., Barrett, G., Neshige, R., Hirata, I. and Tomoda, H. (1986) Volitional movement is not preceded by cortical slow negativity in cerebellar dentate lesion in man. Brain Res., 368, 361–5.

    Article  PubMed  CAS  Google Scholar 

  • Shibasaki, H., Shima, F. and Kuroiwa, Y. (1978) Clinical studies of the movement-related cortical potential (MP) and the relationship between the dentatorubrothalamic pathway and readiness potential (RP). J. Neurol., 219, 15–25.

    Article  PubMed  CAS  Google Scholar 

  • Singh, J. and Knight, R. T. (1990) Frontal lobe contribution to voluntary movements in humans. Brain Res., 531, 45–54.

    Article  PubMed  CAS  Google Scholar 

  • Singh, J. and Knight, R. T. (1993) Effects of posterior association cortex lesions on brain potentials preceding self-initiated movements. J. Neurosci., 13, 1820–9.

    PubMed  CAS  Google Scholar 

  • Tarkka, I. M. and Hallett, M. (1991) The cortical potential related to sensory feedback from voluntary movements shows somatotopic organization of the supplementary motor area. Brain Topogr., 3, 359–63.

    Article  PubMed  CAS  Google Scholar 

  • Tarkka, I. M., Massaquoi, S. and Hallett, M. (1993) Movement-related cortical potentials in patients with cerebellar degeneration. Acta Neurol. Scand., 88, 129–35.

    Article  PubMed  CAS  Google Scholar 

  • Toro, C., Matsumoto, J., Deuschl, G., Roth, B. J. and Hallett, M. (1993) Source analysis of scalp-recorded movement-related electrical potentials. Electroencephalogr. Clin. Neurophysiol., 86, 167–75.

    Article  PubMed  CAS  Google Scholar 

  • Tsujimoto, T., Gemba, H. and Sasaki, K. (1993) Effect of cooling the dentate nucleus of the cerebellum on hand movements of the monkey. Brain Res., 629, 1–9.

    Article  PubMed  CAS  Google Scholar 

  • Tsujimoto, T., Ogawa, M., Tsukada, H., Kakiuchi, T. and Sasaki, K. (1998) Activation of the ventral and mesial frontal cortex of the monkey by self-initiated movement tasks as revealed by positron emission tomography. Neurosci.Lett., 258, 117–20.

    Article  PubMed  CAS  Google Scholar 

  • Turton, A., Wroe, S., Trepte, N., Fraser, C. and Lemon, R. N. (1996) Contralateral and ipsilateral EMG responses to transcranial magnetic stimulation during recovery of arm and hand function after stroke. Electroencephalogr.Clin. Neurophysiol., 101, 316–28.

    Article  PubMed  CAS  Google Scholar 

  • Weeks, R., Gerloff, C., Dalakas, M. C. and Hallett, M. (1999) PET study of visually and non-visually guided finger movements in patients with severe pan-sensory neuropathies and healthy controls. Exp. Brain Res., 128, 291–302.

    Article  PubMed  CAS  Google Scholar 

  • Weiller, C., Chollet, F., Friston, K. J., Wise, R. J. and Frackowiak, R. S. J. (1992) Functional reorganization of the brain in recovery from striatocapsular infarction in man. Ann. Neurol., 31, 463–72.

    Article  PubMed  CAS  Google Scholar 

  • Zentner, J., Hufhagel, A., Pechstein, U., Wolf, H. K. and Schramm, J. (1996) Functional results after resective procedures involving the supplementary motor area. J. Neurosurg., 85, 542–49.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer Science+Business Media New York

About this chapter

Cite this chapter

Gerloff, C. (2003). Movement-Related Cortical Potentials in Patients with Focal Brain Lesions. In: Jahanshahi, M., Hallett, M. (eds) The Bereitschaftspotential. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0189-3_11

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-0189-3_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4958-7

  • Online ISBN: 978-1-4615-0189-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics