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Focal Controlled Drug Delivery pp 3–32Cite as

Biodegradable Polymers for Focal Delivery Systems

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Part of the book series: Advances in Delivery Science and Technology ((ADST))

Abstract

Biodegradable polymers for focal drug delivery application play both structural and functional roles. Delivery via these biodegradable polymeric carriers is one of the simplest and most successful approaches due to its physicochemical properties and biocompatibility of these polymers. Thus, these polymers have been increasingly used as implants, invasive delivery systems, and to deliver drugs to a specific site or body compartment. Biodegradable materials used in clinically tested for focal drug therapy are both from natural origin (gelatin, collagen, hyaluronic acid, etc.) and synthetic origin (prepared from lactic acid, glycolic acid, caprolactone, etc.). This chapter provides a review of both introductory and state-of-the-art information about the polymeric carriers used in focal drug therapy for diseased states that are most exploited for localized treatment.

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Authors and Affiliations

  1. Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, 500037, India

    Wahid Khan & Venu Gopala Swami Challa

  2. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA

    Robert Langer

  3. Faculty of Medicine, Institute of Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel

    Abraham J. Domb

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  1. Wahid Khan
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  2. Venu Gopala Swami Challa
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  3. Robert Langer
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  4. Abraham J. Domb
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  1. School of Pharmacy-Faculty of Medicine The Hebrew University of Jerusalem, Jerusalem, Israel

    Abraham J. Domb

  2. Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Balanagar, Hyderabad, Andhra Pradesh, India

    Wahid Khan

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Khan, W., Challa, V.G.S., Langer, R., Domb, A.J. (2014). Biodegradable Polymers for Focal Delivery Systems. In: Domb, A., Khan, W. (eds) Focal Controlled Drug Delivery. Advances in Delivery Science and Technology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-9434-8_1

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