Abstract
The muscles of the pharynx and larynx subserve critical airway, deglutitive and communication functions. The laryngeal muscles protect the lower airway from invasion and allow voice production for the purposes of communication. The muscles of the pharynx serve deglutitive functions by creating appropriate pressures to receive and propel a bolus and to shape the airway to modulate resonance during voice and speech production. Thus, the laryngeal and pharyngeal muscles are critically important to survival and to communication. The structure and function of these muscles are summarized in Table 9.1. A subset of these muscles will be discussed in this chapter as related to voice, swallowing, and airway functions.
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References
Andrade FA (2010) Extraocular muscle metabolism. In: Dartt DA (ed) Encyclopedia of the eye, vol 2. Academic, Oxford, pp 105–110
Asanau A, Timoshenko AP, Prades JM, Galusca B, Martin C, Feasson L (2011) Posterior cricoarytenoid bellies: relationship between their function and histology. J Voice 25(2):e67–e73
Atkinson JE (1978) Correlation analysis of the physiological factors controlling fundamental voice frequency. J Acoust Soc Am 63(1):211–222
Baer T, Gay T, Niimi S (1976) Control of the fundamental frequency, intensity, and register of phonation. HLSRSR 45/46:205–210
Belafsky PC (2010) Manual control of the upper esophageal sphincter. Laryngoscope 120(suppl 1):S1–S16
Belafsky PC, Rees CJ, Allen J, Leonard RJ (2010) Pharyngeal dilation in cricopharyngeus muscle dysfunction and zenker diverticulum. Laryngoscope 120(5):889–894
Burnett TA, Mann EA, Cornell SA, Ludlow CL (2003) Laryngeal elevation achieved by neuromuscular stimulation at rest. J Appl Physiol 94(1):128–134
Burnett TA, Mann EA, Stoklosa JB, Ludlow CL (2005) Self-triggered functional electrical stimulation during swallowing. J Neurophysiol 94(6):4011–4018
Collett PW, Brancatisano AP, Engel LA (1986) Upper airway dimensions and movements in bronchial asthma. Am Rev Respir Dis 133(6):1143–1149
Collier R (1975) Physiological, correlates of intonation patterns. J Acoust Soc Am 58(1):249–256
Connor NP, Suzuki T, Lee K, Sewall GK, Heisey DM (2002) Neuromuscular junction changes in aged rat thyroarytenoid muscle. Ann Otol Rhinol Laryngol 111:579–586
D’Antona G, Megighian A, Bortolotto S, Pellegrino MA, Marchese-Ragona R, Staffieri A et al (2002) Contractile properties and myosin heavy chain isoform composition in single fibres of human laryngeal muscles. J Muscle Res Cell Motil 23(3):187–195
Davis MV, Merati AL, Jaradeh SS, Blumin JH (2007) Myosin heavy chain composition and fiber size of the cricopharyngeus muscle in patients with achalasia and normal subjects. Ann Otol Rhinol Laryngol 116:643–646
DelGaudio JM, Sciote JJ, Carroll WR, Escalmado RM (1995) Atypical myosin heavy chain in rat laryngeal muscle. Ann Otol Rhinol Laryngol 104(3):237–245
Erickson D, Liberman M, Niimi S (1977) The geniohyoid and the role of the strap muscle. Haskins Lab Status Report in Speech Research (HLSRSR) SR-49:103–110
Faaborg-Andersen K (1957) Electromyographic investigation of intrinsic laryngeal muscles in humans. Acta Physiol Scand 140S:1–149
Faaborg-Andersen K, Sonninen A (1960) The function of the extrinsic laryngeal muscles at different pitch: an electromyographic and roentgenologic investigation. Acta Otolaryngol 51:89–93
Feinstein B, Lindegard B, Nyman E, Wohlfart G (1955) Morphologic studies of motor units in normal human muscles. Acta Anat 23:127–142
Gambino DR, Malmgren LT, Gacek RR (1990) Age-related changes in the neuromuscular junctions in the human posterior cricoarytenoid muscles: a quantitative study. Laryngoscope 100:262–268
Goyal RK, Martin SB, Shapiro J, Spechler SJ (1993) The role of cricopharyngeus muscle in pharyngoesophageal disorders. Dysphagia 8(3):252–258
Halum SL, Shemirani NL, Merati AL, Jaradeh S, Toohill RJ (2006) Electromyography findings of the cricopharyngeus in association with ipsilateral pharyngeal and laryngeal muscles. Ann Otol Rhinol Laryngol 115(4):312–316
Hammond CS, Davenport PW, Hutchison A, Otto RA (1997) Motor innervation of the cricopharyngeus muscle by the recurrent laryngeal nerve. J Appl Physiol 83(1):89–94
Han Y, Wang J, Fischman DA, Biller HF, Sanders I (1999) Slow tonic muscle fibers in the thyroarytenoid muscles of human vocal folds: a possible specialization for speech. Anat Rec 256(2):146–157
Hast MH (1969) The primate larynx: a comparative physiological study of intrinsic muscles. Acta Otolaryngol 67:84–92
Hinrichsen C, Dulhunty A (1982) The contractile properties, histochemistry, ultrastructure and electrophysiology of the cricothyroid and posterior cricoarytenoid muscles in the rat. J Muscle Res Cell Motil 3(2):169–190
Hirano M (1969) Recent advance in laryngeal electromyography in human. Kurume Med J 16(3):119–126
Hiss SG, Huckabee ML (2005) Timing of pharyngeal and upper esophageal sphincter pressures as a function of normal and effortful swallowing in young healthy adults. Dysphagia 20(2):149–156
Hixon TJ, Weismer G, Hoit JD (2008) Preclinical speech science. Plural Publishing, San Diego
Hoffman MR, Ciucci MR, Mielens JD, Jiang JJ, McCulloch TM (2010) Pharyngeal swallow adaptations to bolus volume measured with high-resolution manometry. Laryngoscope 120:2367–2373
Hoh JF (2005) Laryngeal muscle fibre types. Acta Physiologica Scandinavica 183(2):133–149
Hong KH, Ye M, Kim YM, Kevorkian KF, Berke GS (1997) The role of strap muscles in phonation—in vivo canine laryngeal model. J Voice 11(1):23–32
Hwang K, Grossman MI, Ivy AC (1948) Nervous control of the cervical portion of the esophagus. Am J Physiol 154(2):343–357
Inagi K, Schultz E, Ford CN (1998) An anatomic study of the rat larynx: establishing the rat model for neuromuscular function. Otolaryngol Head Neck Surg 118:74–81
Jung HH, Han SH, Choi JO (1999) Expression of myosin heavy chain mRNA in rat laryngeal muscles. Acta Otolaryngol 119(3):396–402
Kahrilas PJ (1997) Upper esophageal sphincter function during anterograde and retrograde transit. Am J Med 103(5A):56S–60S
Kenyon EL (1992) Significance of the extrinsic musculature of the larynx. J Am Med Assoc 79:428–431
Kersing W, Jennekens FG (2004) Age-related changes in human thyroarytenoid muscles: a histological and histochemical study. Eur Arch Otorhinolaryngol 261(7):386–392
Kirchner JA (1958) The motor activity of the cricopharyngeus muscle. Laryngoscope 68(7):1119–1159
Kuna ST, Insalaco G (1990) Respiratory-related intrinsic laryngeal muscle activity in normal adults. Prog Clin Biol Res 345:117–124
Kuna ST, Insalaco G, Woodson GE (1988) Thyroarytenoid muscle activity during wakefulness and sleep in normal adults. J Appl Physiol 65(3):1332–1339
Kuna ST, Smickley JS, Insalaco G (1990) Posterior cricoarytenoid muscle activity during wakefulness and sleep in normal adults. J Appl Physiol 68(4):1746–1754
Kuna ST, Insalaco G, Villeponteaux RD (1991) Arytenoideus muscle activity in normal adult humans during wakefulness and sleep. J Appl Physiol 70(4):1655–1664
Lang IM, Shaker R (1997) Anatomy and physiology of the upper esophageal sphincter. Am J Med 103(5A):50S–55S
Lund WS (1965) A study of the cricopharyngeal sphincter in man and in the dog. Ann R Coll Surg Engl 37(4):225–246
Lundy DS, Smith C, Colangelo L, Sullivan PA, Logemann JA, Lazarus CL et al (1999) Aspiration: cause and implications. Otolaryngol Head Neck Surg 120(4):474–478
Mathieu-Costello O, Szewczak JM, Logemann RB, Agey PJ (1992) Geometry of blood-tissue exchange in bat flight muscle compared with bat hindlimb and rat soleus muscle. Am J Physiol 262(6 pt 2):R955–R965
McCulloch TM, Hoffman MR, Ciucci MR (2010) High-resolution manometry of pharyngeal swallow pressure events associated with head turn and chin tuck. Ann Otol Rhinol Laryngol 119(6):369–376
McMullen CA, Andrade FH (2006) Contractile dysfunction and altered metabolic profile of the aging rat thyroarytenoid muscle. J Appl Physiol 100(2):602–608
McMullen CA, Andrade FH (2009) Functional and morphological evidence of age-related denervation in rat laryngeal muscles. J Gerontol A Biol Sci Med Sci 64:435–442
Merati AL, Bodine SC, Bennett T, Jung H-H, Furuta H, Ryan AF (1996) Identification of a novel myosin heavy chain gene expressed in the rat larynx. Biochim Biophys Acta 1306:153–159
Mu L, Sanders I (1998) Neuromuscular organization of the human upper esophageal sphincter. Ann Otol Rhinol Laryngol 107(5 pt 1):370–377
Mu L, Sanders I (2002) Muscle fiber-type distribution pattern in the human cricopharyngeus muscle. Dysphagia 17:87–96
Nagai H, Ota F, Connor NP (2005) Effect of deficits in laryngeal sensation on laryngeal muscle biochemistry. Ann Otol Rhinol Laryngol 114(5):352–360
Nasri S, Beizai P, Ye M, Sercarz JA, Kim YM, Berke GS (1997) Cross-innervation of the thyroarytenoid muscle by a branch from the external division of the superior laryngeal nerve. Ann Otol Rhinol Laryngol 106:594–598
Niimi S, Horiguchi S, Kobayashi N (1991) F0 raising role of the sternothyroid muscle—an electromyographic study of two tenors. In: Gauffin NJ, Hammarberg B (eds) Vocal fold physiology. Singular Publishing Group, San Diego, pp 183–188
Palmer J (1989) Electromyography of the muscles of oropharyngeal swallowing: basic concepts. Dysphagia 3:192–198
Perie S, St Guily JL, Callard P, Sebille A (1997) Innervation of adult human laryngeal muscle fibers. J Neurol Sci 149:81–86
Perie S, St Guily JL, Sebille A (1999) Comparison of perinatal and adult multi-innervation in human laryngeal muscle fibers. Ann Otol Rhinol Laryngol 108(7 pt 1):683–688
Perie S, Agbulut O, St Guily JL, Butler-Browne GS (2000) Myosin heavy chain expression in human laryngeal muscle fibers. A biochemical study. Ann Otol Rhinol Laryngol 109(2):216–220
Plant RL (1998) Anatomy and physiology of swallowing in adults and geriatrics. Otolaryngol Clin North Am 31(3):477–488
Powers S, Howley E (2004) Exercise physiology: theory and application to fitness and performance, 5th edn. McGraw-Hill, New York
Ren M, Mu L (2005) Intrinsic properties of the adult human mylohyoid muscle: neural organization, fiber-type distribution, and myosin heavy chain expression. Dysphagia 20:182–194
Rosen M, Malmgren LT, Gacek RR (1983) Three-dimensional computer reconstruction of the distribution of neuromuscular junctions in the thyroarytenoid muscle. Ann Otol Rhinol Laryngol 92:424–429
Rosenfield DB, Miller RH, Sessions RB, Patten BM (1982) Morphologic and histochemical characteristics of laryngeal muscle. Arch Otolaryngol 108(10):662–666
Sanders I, Mu L (1998) Anatomy of the human internal superior laryngeal nerve. Anat Rec 252:646–656
Sanders I, Mu L, Wu BL, Biller HF (1993) The intramuscular nerve supply of the human lateral cricoarytenoid muscle. Acta Otolaryngol 113(5):679–682
Sanes JR, Lichtman JW (1999) Development of the vertebrate neuromuscular junction. Annu Rev Neurosci 22:389–442
Sapir S, Campbell C, Larson C (1981) Effect of geniohyoid, cricothyroid and sternothyroid muscle stimulation on voice fundamental frequency of electrically elicited phonation in rhesus macaque. Laryngoscope 91(3):457–468
Sasaki CT, Kim YH, Sims HS, Czibulka A (1999) Motor innervation of the human cricopharyngeus muscle. Ann Otol Rhinol Laryngol 108(12):1132–1139
Sciote JJ, Morris TJ, Brandon CA, Horton MJ, Rosen C (2002) Unloaded shortening velocity and myosin heavy chain variations in human laryngeal muscle fibers. Ann Otol Rhinol Laryngol 111(2):120–127
Shin T, Hirano M, Maeyama T, Nozoe I, Ohkubo H (1981) The function of the extrinsic laryngeal muscles. In: Stevens K, Hirano M (eds) Vocal fold physiology. Tokyo: University of Tokyo Press, pp 171–180
Shiotani A, Flint PW (1998a) Expression of extraocular-superfast-myosin heavy chain in rat laryngeal muscles. Neuroreport 9(16):3639–3642
Shiotani A, Flint PW (1998b) Myosin heavy chain composition in rat laryngeal muscles after denervation. Laryngoscope 108(8 pt 1):1225–1229
Shiotani A, Jones RM, Flint PW (1999a) Postnatal development of myosin heavy chain isoforms in rat laryngeal muscles. Ann Otol Rhinol Laryngol 108(5):509–515
Shiotani A, Westra WH, Flint PW (1999b) Myosin heavy chain composition in human laryngeal muscles. Laryngoscope 109(9):1521–1524
Shipp T (1975) Vertical laryngeal position during continuous and discrete vocal frequency change. J Speech Hear Res 18:707–718
Sonninen AA (1956) The role of the external laryngeal muscles in length-adjustment of the vocal cords in singing: phoniatric, roentgenologic and experimental studies of the mechanism of pitch change in the voice with special reference to the function of the sternothyroid. Acta Otolaryngol Suppl 130:1–102
Soussi-Yanicostas N, Barbet JP, Laurent-Winter C, Barton P, Butler-Browne GS (1990) Transition of myosin isozymes during development of human masseter muscle: persistence of developmental isoforms during postnatal stage. Development 108(2):239–249
Sundman E, Ansved T, Margolin G, Kuylenstierna R, Eriksson LI (2004) Fiber-type composition and fiber size of the human cricopharyngeal muscle and the pharyngeal constrictor muscle. Acta Anaesthesiol Scand 48:423–429
Suzuki T, Connor NP, Lee K, Bless DM, Ford CN, Inagi K (2002) Age-related alterations in myosin heavy chain isoforms in rat intrinsic laryngeal muscles. Ann Otol Rhinol Laryngol 111(11):962–967
Titze IR (1994) Principles of voice production. Prentice Hall, Englewood Cliffs, NJ
Ueda N, Ohyama M, Harvey J, Ogura J (1972) Influence of certain extrinsic laryngeal muscles on artificial voice production. Laryngoscope 82:468–482
Vaiman M, Eviatar E, Segal S (2004) Evaluation of normal deglutition with the help of rectified surface electromyography records. Dysphagia 19(2):125–132
Van Daele DJ, McCulloch TM, Palmer PM, Langmore SE (2005) Timing of glottic closure during swallowing: a combined electromyographic and endoscopic analysis. Ann Otol Rhinol Laryngol 114(6):478–487
van Lunteren E, Strohl KP (1986) The muscles of the upper airways. Clin Chest Med 7(2): 171–188
Vilkman E, Sonninen A, Hurme P, Korkko P (1996) External laryngeal frame function in voice production revisited: a review. J Voice 10(1):78–92
Widmaier EP, Raff H, Strang KT (2004) Vander, Sherman, and Luciano’s human physiology: the mechanisms of body function, 9th edn. McGraw-Hill, Boston
Wieczorek DF, Periasamy M, Butler-Browne GS, Whalen RG, Nadal-Ginard B (1985) Co-expression of multiple myosin heavy chain genes, in addition to a tissue-specific one, in extraocular musculature. J Cell Biol 101(2):618–629
Woodson G (1999) Laryngeal and pharyngeal function part one: breathing and speech. In: Cummings CW, Fredrickson JM, Harker LA, Krause CJ, Richardson MA, Schuller DE (eds) Otolaryngology head and neck surgery, 3rd edn. Mosby, St. Louis
Wu YZ, Baker MJ, Crumley RL, Blanks RH, Caiozzo VJ (1998) A new concept in laryngeal muscle: multiple myosin isoform types in single muscle fibers of the lateral cricoarytenoid. Otolaryngol Head Neck Surg 118(1):86–94
Wu YZ, Crumley RL, Armstrong WB, Caiozzo VJ (2000) New perspectives about human laryngeal muscle: single-fiber analyses and interspecies comparisons. Arch Otolaryngol Head Neck Surg 126(7):857–864
Yoshihara T, Ishii T, Iwata M, Nomoto M (1998) Ultrastructural and histochemical study of the motor end plates of the intrinsic laryngeal muscles in amyotrophic lateral sclerosis. Ultrastruct Pathol 22:121–126
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Vinney, L.A., Connor, N.P. (2012). Structure and Function of the Laryngeal and Pharyngeal Muscles. In: McLoon, L., Andrade, F. (eds) Craniofacial Muscles. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4466-4_9
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