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Bioceramics for Osteogenesis, Molecular and Cellular Advances

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Regenerative Biology of the Spine and Spinal Cord

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 760))

Abstract

The remarkable need for bone tissue replacement in clinical situations, its limited availability and some major drawbacks of autologous (from the patient) and allogeneic (from a donor) bone grafts are driving researchers to search for alternative approaches for bone repair. In order to develop an appropriate bone substitute, one should understand bone structure and properties and its growth, which will guide researchers to select the optimal conditions for tissue culture and implantation. It’s well accepted that bioceramics are excellent candidates as bone replacement with osteogenesis, osteoinduction and osteoconduction capacity. Therefore, the molecular and cellular interactions that take place at the surface of bioceramics and their relevance in osteogenesis excites many researchers to delve deeper into this line of research.

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Authors and Affiliations

  1. Research and Development Laboratory, Alvimedica Medical Technologies, Çatalca, Istanbul, Turkey

    Hande Demirkiran

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  1. Hande Demirkiran
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Editors and Affiliations

  1. Division of Neurosurgery, City of Hope Cancer Center and Beckman Research Institute, Los Angeles, California, USA

    Rahul Jandial MD, PhD  & Mike Y. Chen MD, PhD  & 

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Demirkiran, H. (2012). Bioceramics for Osteogenesis, Molecular and Cellular Advances. In: Jandial, R., Chen, M.Y. (eds) Regenerative Biology of the Spine and Spinal Cord. Advances in Experimental Medicine and Biology, vol 760. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4090-1_9

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