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Hydrogels

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Fundamentals and Applications of Controlled Release Drug Delivery

Part of the book series: Advances in Delivery Science and Technology ((ADST))

Abstract

Hydrogels are crosslinked polymers with the ability to swell in an aqueous medium. Crosslinking in hydrogels occurs by chemical or physical means depending on the polymer properties and experimental conditions. Owing to a large variety in chemical structure and crosslinking methods, various hydrogels have been prepared for various applications in pharmaceutical and biomedical fields. This chapter begins with hydrogel classification, properties, and their methods of preparation. The chapter continues with intelligent hydrogels, which are able to respond to environmental changes such as temperature, pH, and solvent composition, by changing their dimensions. Hydrogel based on polysaccharides, hydrocolloids, and synthetic polymers are discussed accordingly. Finally, the chapter concludes with known hydrogel applications in the pharmaceutical area. These include superdisintegrants, ion exchanging resins, superporous hydrogels, hydrogel implants, hydrogel inserts, osmotic products (devices, implants, and tablets), as well as tissue expanding hydrogels and contact lenses.

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Authors and Affiliations

  1. Health Professions Division, College of Pharmacy, Nova Southeastern University, 3200 S. University Drive, Fort Lauderdale, FL, USA

    Hossein Omidian

  2. Departments of Biomedical Engineering and Pharmaceutics, Purdue University, West Lafayette, IN, USA

    Kinam Park

Authors
  1. Hossein Omidian
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  2. Kinam Park
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Correspondence to Hossein Omidian .

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Editors and Affiliations

  1. Rue Maurice Schumann 3, Phalempin, 59133, France

    Juergen Siepmann

  2. , Department of Pharmaceutics, University of Minnesota, Harvard Street SE 308, Minneapolis, 55455, Minnesota, USA

    Ronald A. Siegel

  3. , School of Pharmacy, Griffith University, Parklands Drive 1, Southport, 4215, Queensland, Australia

    Michael J. Rathbone

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Omidian, H., Park, K. (2012). Hydrogels. In: Siepmann, J., Siegel, R., Rathbone, M. (eds) Fundamentals and Applications of Controlled Release Drug Delivery. Advances in Delivery Science and Technology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-0881-9_4

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