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Antigen Specific T Cell Factors in the Genetic Control of the Immune Response to Poly(Tyr, Glu)-Poly(Pro)—Poly(Lys)

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Abstract

The antibody response of mice to poly(LTyr, LGlu)-poly(LPro)—poly(LLys), abbreviated (T, G)-Pro—L, is specific for the Pro—L region of the immunogen and is genetically controlled. SJL mice are high responders to this immunogen, whereas DBA/1 and SWR mice are low responders. DBA/1 mice do not produce antibodies to Pro—L, but respond well to antigenic determinants attached to this moiety, while SWR mice do not respond to Pro—L or to any determinant attached to this carrier.

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References

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© 1976 Plenum Press, New York

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Mozes, E., Isac, R. (1976). Antigen Specific T Cell Factors in the Genetic Control of the Immune Response to Poly(Tyr, Glu)-Poly(Pro)—Poly(Lys). In: Feldman, M., Globerson, A. (eds) Immune Reactivity of Lymphocytes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4355-4_85

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  • DOI: https://doi.org/10.1007/978-1-4613-4355-4_85

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4357-8

  • Online ISBN: 978-1-4613-4355-4

  • eBook Packages: Springer Book Archive

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