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Conjugative Sex Plasmids of Streptomyces

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Abstract

Much is known about the ways in which the conjugative plasmids of gram-negative bacteria cause their hosts to mate (1). Detailed knowledge has been obtained about how the transfer of plasmid DNA occurs (2). The mechanisms by which such plasmids promote the mobilization of chromosomal genes have also been extensively studied (3–6). In contrast, very little is known about such phenomena for Streptomyces plasmids (7). However, now that many Steptomyces plasmids can be isolated with ease (8), genetically manipulated in vitro, and returned to the host cells by transformation of protoplasts (9,10) we can hope for more rapid progress in the understanding of the molecular biology of these plasmids. Here we review some facts and ideas about Streptomyces conjugation which may serve as a basis for future experimentation. As we see, conjugative Streptomyces plasmids are likely to possess properties interestingly different from those of plasmids of gram-negative bacteria and so they should repay a detailed investigation.

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Author information

Authors and Affiliations

  1. John Innes Institute, Colney Lane, Norwich, NR4 7UH, England

    D. A. Hopwood, D. J. Lydiate, F. Malpartida & H. M. Wright

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  1. D. A. Hopwood
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  2. D. J. Lydiate
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  3. F. Malpartida
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  4. H. M. Wright
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Editor information

Editors and Affiliations

  1. University of California, San Diego, La Jolla, California, USA

    Donald R. Helinski

  2. Stanford University, Stanford, California, USA

    Stanley N. Cohen

  3. University of Michigan, Ann Harbor, Michigan, USA

    Don B. Clewell

  4. Genex Corporation, Gaithersburg, Maryland, USA

    David A. Jackson

  5. Council for Research Planning in Biological Sciences, Inc., Washington, D.C., USA

    Alexander Hollaender

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© 1985 Plenum Press, New York

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Hopwood, D.A., Lydiate, D.J., Malpartida, F., Wright, H.M. (1985). Conjugative Sex Plasmids of Streptomyces . In: Helinski, D.R., Cohen, S.N., Clewell, D.B., Jackson, D.A., Hollaender, A. (eds) Plasmids in Bacteria. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2447-8_43

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  • DOI: https://doi.org/10.1007/978-1-4613-2447-8_43

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9487-0

  • Online ISBN: 978-1-4613-2447-8

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