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Frequent Detection of Erythroid and Platelet Antigens in Myeloid Blast Crisis of CML

  • Conference paper
Leukocyte Typing II

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Abstract

The terminal phase of chronic myeloid leukemia (CML) is often characterized by an accumulation of immature cells. The differentiation stage of these immature cells can vary considerably, however.

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References

  1. Bettelheim, P., D. Lutz, O. Majdic, E. Paietta, O. Haas, W. Linkesch, E. Neumann, L. Lechner, and W. Knapp. 1985. Cell lineage heterogeneity in blast crisis of chronic myeloid leukaemia. Brit. J. Haematol., 59: 395.

    Article  CAS  Google Scholar 

  2. Bettelheim, P., E. Paietta, O. Majdic, H. Gadner, J. Schwarzmeier, and W. Knapp. 1982. Expression of a myeloid marker on TdT-positive acute lymphocytic leukemic cells: evidence by double-fluorescence staining. Blood 60: 1392.

    PubMed  CAS  Google Scholar 

  3. Majdic, O., K. Liszka, D. Lutz, and W. Knapp. 1981. Myeloid differentiation antigen defined by a monoclonal antibody. Blood 58: 1127.

    PubMed  CAS  Google Scholar 

  4. Majdic, O., P. Bettelheim, H. Stockinger, W. Aberer, K. Liszka, D. Lutz, and W. Knapp. 1984. M2, a novel myelomonocytic cell surface antigen and its distribution on leukemic cells. Int. J. Cancer 33: 617.

    Article  PubMed  CAS  Google Scholar 

  5. Knapp, W., O. Majdic, H. Stockinger, P. Bettelheim, K. Liszka, U. Koller, and C. Peschel. 1984. Monoclonal antibodies to human myelomonocytic differentiation antigens in the diagnosis of acute myeloid leukemia. Med. Oncol. Tum. Pharmacother., 1: 257.

    CAS  Google Scholar 

  6. Sugimoto, T., E. Tatsumi, K. Takeda, K. Minato, K. Sagawa, and I. Minowada. 1984. Modulation of cell surface antigens induced by 12-O-tetradeca- noylphorbol 13-acetate in two myeloblasts cell lines, a promyelocyte cell line, and a monoblastic cell line: Detection with five monoclonal antibodies. J. Natl. Cancer Inst. 72: 923.

    PubMed  CAS  Google Scholar 

  7. Griffin, J.D., and S.F. Schlossman. 1984. Expression of myeloid differentiation antigens in acute myeloblasts leukemia. In: Leucocyte typing, A. Bernard, L. Boumsell, J. Dausset, C. Milstein, and S.F. Schlossman, eds. Springer-Verlag, Berlin, Heidelberg, p. 404–410.

    Google Scholar 

  8. Ugolini, V., G. Nunez, R.G. Smith, P. Stastny, and J.D. Capra. 1980. Initial characterization of monoclonal antibodies against human monocytes. Proc. Natl Acad. Sei. U.S.A. 77: 6764.

    Article  CAS  Google Scholar 

  9. Majdic, O., P. Bettelheim, K. Liszka, and D. Lutz. 1982. Leukämiediagnostik mit monoklonalen Antikörpern. Wr. Klin. Wochenschr. 94: 387.

    CAS  Google Scholar 

  10. Liszka, K., O. Majdic, P. Bettelheim, and W. Knapp. 1983. Glycophorin A expression in malignant hematopoiesis. Am. J. Haematol. 15: 219.

    Article  CAS  Google Scholar 

  11. Anstee, D.J., and P.A.W. Edwards. 1982. Monoclonal antibodies to human erythrocytes. Eur. J. Immunol. 12: 228.

    Article  PubMed  CAS  Google Scholar 

  12. McMichael, A.J., N.A. Rust, J.R. Pilch, R. Sochynsky, J. Morton, D.Y. Mason, C. Ruan, G. Tobelem, and J. Caen. 1981. Monoclonal antibody to human platelet glycoprotein I. Brit. J. Haematol. 49: 501.

    Article  CAS  Google Scholar 

  13. Vainchenker, W., J.F. Deschamps, J.M. Bastin, J. Guichard, M. Titeux, J. Breton-Gorius, and A.J. McMichael. 1982. Two monoclonal antiplatelet antibodies as markers of human megakaryocyte maturation: immunofluorescent staining and platelet peroxidase detection in megakaryocyte colonies and in vivo cells from normal and leukemic patients. Blood 59: 514.

    PubMed  CAS  Google Scholar 

  14. Tetteroo, P.A.T., P.M. Lansdorp, O.C. Leeksma, and A.E.G.K. von dem Borne. 1982. Monoclonal antibodies against human platelet glycoprotein Ilia. Brit. J. Haematol. 55: 509.

    Google Scholar 

  15. Tetteroo, P.A.T., F. Massaro, A. Muder, R. Schreuder van Gelder, and A.E.G.K. von dem Borne. 1984. Megakaryoblastic differentiation of pro- erythroblystic K562 cell-line cells. Leuk. Res., 8: 197.

    Article  PubMed  CAS  Google Scholar 

  16. Vodinelich, L., W. Tax, Y. Bai, S. Pegram, P. Capel, and M.F. Greaves. 1983. A monoclonal antibody (WT1) for detecting leukemias of T-cell precursors (T-ALL). Blood 62: 1108.

    PubMed  CAS  Google Scholar 

  17. Reinherz, E.L., P.C. Kung, G. Goldstein, and S.F. Schlossman. 1979. A monoclonal antibody with selective reactivity with functionally mature human thymocytes and all peripheral human T cells. J. Immunol. 123: 1312.

    PubMed  CAS  Google Scholar 

  18. Kung, P.C., M.A. Talle, M. DeMaria, M. Butler, J. Lifter, and G. Goldstein. 1980. Strategies for generating monoclonal antibodies defining human T lymphocyte differentiation antigens. Transplant. Proc. 12 (suppl.): 141.

    PubMed  CAS  Google Scholar 

  19. Kamoun, M., P.J. Martin, J.A. Hansen, M.A. Brown, A.W. Siedak, and R.C. Nowinski. 1981. Identification of a human T lymphocyte surface protein associated with the E-rosette receptor. J. Exp. Med. 153: 207.

    Article  PubMed  CAS  Google Scholar 

  20. McMichael, A.J., J.R. Rilch, G. Galfre, D.Y. Mason, J.W. Fabre, and C. Milstein. 1979. A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur. J. Immunol. 9: 205.

    Article  PubMed  CAS  Google Scholar 

  21. Ledbetter, J.A., R.L. Evans, M. Lipinski, C. Cunningham-Rundles, R.A. Good, and L.A. Herzenberg. 1981. Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and T cytotoxic/suppressor subpopulations in mouse and man. J. Exp. Med. 153: 310.

    Article  PubMed  CAS  Google Scholar 

  22. Evans, R.L., D.W. Wall, C.D. Platsoucas, F.P. Siegal, S.M. Fikrig, C.M. Testa, and R.A. Good. 1981. Thymus-dependent membrane antigens in man: Inhibition of cell-mediated lympholysis by monoclonal antibodies to Th2 antigens. Proc. Natl. Acad. Sci. U.S.A. 78: 544.

    Article  PubMed  CAS  Google Scholar 

  23. Knapp, W., O. Majdic, P. Bettelheim, and K. Liszka. 1982. VIL-A1, a monoclonal antibody reactive with common acute lymphatic leukemia cells. Leuk. Res. 6: 137.

    Article  PubMed  CAS  Google Scholar 

  24. Forster, K.K., F.G. Gudat, Marie F. Girard, Renate Albrecht, J. Schmidt, C. Ludwig, and J.-P. Obrecht. 1982. Monoclonal antibody against a membrane antigen characterizing leukemic human B-lymphocytes. Cancer Res. 42: 1927.

    PubMed  CAS  Google Scholar 

  25. Greaves, M.F., C. Sieff, and P.A.W. Edwards. 1983. Monoclonal anti-glycophorin as a probe for erythroleukemias. Blood 61: 645.

    PubMed  CAS  Google Scholar 

  26. Bai, Y., H. Durbin, and N. Hogg. 1984. Monoclonal antibodies specific for platelet glycoproteins react with human monocytes. Blood 64: 139.

    PubMed  CAS  Google Scholar 

  27. Robinson, J., C. Sieff, D. Delia, P.A.W. Edwards, and M. Greaves. 1981. Expression of cell-surface HLA-DR, HLA-ABC and glycophorin during erythroid differentiation. Nature 289: 68.

    Article  PubMed  CAS  Google Scholar 

  28. Hughes, A., B.A. McVerry, H. Walker, K.F. Bradstock, A.V. Hoffbrand, and G. Janossy. 1981. Heterogeneous blast cell crisis in Philadelphia negative chronic granulocytic leukaemia. Brit. J. Haematol. 47: 563.

    Article  CAS  Google Scholar 

  29. Greaves, M.F. 1982. Target cells differentiation and clonal evolution in chronic granulocytic leukemia: a ‘model’ for understanding the biology of malignancy. In: Chronic granulocytic leukemia. M.T. Shaw, ed. Praeger, New York, p. 15–47.

    Google Scholar 

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Authors
  1. P. Bettelheim
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  2. D. Lutz
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  3. O. Majdic
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  4. O. Haas
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  5. W. Knapp
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Editor information

Editors and Affiliations

  1. Division of Tumor Immunology, Dana-Farber Cancer Institute, 02115, Boston, MA, USA

    Ellis L. Reinherz M.D.  & Lee M. Nadler M.D.  & 

  2. Department of Medicine, Duke Univeristy School of Medicine, 27710, Durham, NC, USA

    Barton F. Haynes M.D.

  3. Program in Pediatric Oncology, Fred Hutchinson Cancer Research Center, 98104, Seattle, WA, USA

    Irwin D. Bernstein M.D.

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© 1986 Springer-Verlag New York Inc.

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Bettelheim, P., Lutz, D., Majdic, O., Haas, O., Knapp, W. (1986). Frequent Detection of Erythroid and Platelet Antigens in Myeloid Blast Crisis of CML. In: Reinherz, E.L., Nadler, L.M., Haynes, B.F., Bernstein, I.D. (eds) Leukocyte Typing II. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4850-7_25

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  • DOI: https://doi.org/10.1007/978-1-4612-4850-7_25

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-9329-3

  • Online ISBN: 978-1-4612-4850-7

  • eBook Packages: Springer Book Archive

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