Abstract
Numerous studies suggest that the patterned motor responses of drinking and swallowing are organized at the brainstem level (reviewed in Berntson and Micco 1976). Decerebration experiments further indicate that tactile and gustatory receptors can modify fluid intake using brainstem mechanisms, but that drinking to correct a water imbalance and spontaneous drinking both require an intact forebrain (Grill and Miselis 1981). Because only a fraction of an animal’s behaviour is evident when the forebrain and hindbrain are disconnected, decerebrate preparations provide an experimental method for establishing a gross anatomical location for function. Careful behavioural testing reveals those sensory and motor capacities that are intact, thereby allowing anatomical and physiological studies to be interpreted within the context of a limited, but specific, behavioural repertoire. The first section of this chapter reviews the sensorimotor capacity of the decerebrate preparation with respect to ingestive behaviour. This is followed by several sections discussing brainstem pathways mediating these responses.
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References
Altschuler SM, Bao X, Bieger D, Hopkins DA, Miselis RR (1989) Viscerotopic representation of the upper alimentary tract in the rat: sensory ganglia and nuclei of the solitary and spinal trigeminal tracts. J Comp Neurol 283:248–268
Amano N, Hu JW, Sessle BJ (1986) Responses of neurons in feline trigeminal subnucleus caudalis (medullary dorsal horn) to cutaneous, intraoral, and muscle afferent stimuli. J Neurophysiol 55:227–243
Amri M, Car A (1988) Projections from the medullary swallowing center to the hypoglossal motor nucleus: a neuroanatomical and electrophysiological study in sheep. Brain Res 441:119–126
Amri M, Car A, Jean A (1984) Medullary control of the pontine swallowing neurones in sheep. Exp Brain Res 55:105–110
Beckstead RM, Domesick VB, Nauta WJH (1979) Efferent connections of the substantia nigra and ventral tegmental area in the rat. Brain Res 175:191–217
Berntson GG, Micco DJ (1976) Organization of brainstem behavioral systems. Brain Res Bull 1:471–483
Bieger D (1984) Muscarinic activation of rhombencephalic neurones controlling oesophageal peristalsis in the rat. Neuropharmacology 23:1451–1464
Bignall KE, Schramm L (1974) Behavior of chronically decerebrated kittens. Exp Neurol 42:519–531
Borke RC, Nau ME, Ringler RL Jr (1983) Brain stem afferents of hypoglossal neurons in the rat. Brain Res 269:47–55
Car A, Amri M (1982) Etude des neurones deglutiteurs pontiques chez la brebis: I. Activite et localisation. Exp Brain Res 48:345–354
Car A, Amri M (1987) Activity of neurons located in the region of the hypoglossal motor nucleus during swallowing in sheep. Exp Brain Res 69:175–182
Carrive P, Bandler R, Dampney RAL (1989) Viscerotopic control of regional vascular beds by discrete groups of neurons within the midbrain periaqueductal gray. Brain Res 493:385–390
Chandler SH, Goldberg LJ (1984) Differentiation of the neural pathways mediating cortically induced and dopaminergic activation of the central pattern generator (CPG) for rhythmical jaw movements in the anesthetized guinea pig. Brain Res 323:297–301
Chandler SH, Tal M (1986) The effects of brain stem transections on the neuronal networks responsible for rhythmical jaw muscle activity in the guinea pig. J Neurosci 6:1831–1842
Chandler SH, Tal M (1987) Brain-stem perturbations during cortically evoked rhythmical jaw movements: effects of activation of brain-stem loci on jaw muscle cycle characteristics. J Neurosci 7:463–472
Chronister RB, Walding JS, Aides LD, Marco LA (1988) Interconnections between substantia nigra reticulata and medullary reticular formation. Brain Res Bull 21:313–317
Dellow PG, Lund JP (1971) Evidence for central timing of rhythmical mastication. J Physiol 215:1–13
Dostrovsky JO, Hu JW, Sessle BJ, Sumino R. (1982) Stimulation sites in periaqueductal gray, nucleus raphe magnus and adjacent regions effective in suppressing oral-facial reflexes. Brain Res 252:287–297
Ermirio R, Guggeri P, Blanchi D, Cogo CE, Bergaglio M (1989) Effects of intraoral mechanoreceptor stimulation on reticular formation neurones in the rabbit. Arch Ital Biol 127:1–11
Gerstner GE, Goldberg LJ, De Bruyne K (1989) Angiotensin Il-induced rhythmic jaw movements in the ketamine-anesthetized guinea pig. Brain Res 478:233–240
Grill HJ (1986) Caudal brainstem contributions to the integrated neural control of energy homeostasis. In: Ritter RC (ed) Feeding behavior: neural and hormonal controls. Academic Press, New York, pp 103–129
Grill HJ, Miselis RR (1981) Lack of ingestive compensation to osmotic stimuli in chronic decerebrate rats. Am J Physiol 240:81–86
Grill HJ, Norgren R (1978) Chronically decerebrate rats demonstrate satiation but not bait shyness. Science 201:267–269
Grill HJ, Schulkin J, Flynn FW (1986) Sodium homeostasis in chronic decerebrate rats. Behav Neurosci 100:536–543
Hashim MA, Bieger D (1989) Excitatory amino acid receptor-mediated activation of solitarial deglutitive loci. Neuropharmacology 28:913–921
Hayama T, Ito S, Ogawa H (1987) Receptive field properties of the parabrachio-thalamic taste and mechanoceptive neurons in rats. Exp Brain Res 68:458–465
Hermann GE, Rogers RC (1985) Convergence of vagal and gustatory afferent input within the parabrachial nucleus of the rat. J Auton Nerv Syst 13:1–17
Hiraba K, Taira M, Sahara Y, Nakamura Y (1988) Single-unit activity in bulbar reticular formation during food ingestion in chronic cats. J Neurophysiol 60:1333–1349
Holstege G (1987) Some anatomical observations on the projections from the hypothalamus to brainstem and spinal cord: an HRP and autoradiographic tracing study in the cat. J Comp Neurol 260:98–126
Jean A (1984) Control of the central swallowing program by inputs from the peripheral receptors. A review. J Auton Nerv Syst 10:225–233
Jean A, Car A, Roman C (1975) Comparison of activity in pontine versus medullary neurones during swallowing. Exp Brain Res 22:211–220
Joseph JP, Boussaoud D, Biguer B (1985) Activity of neurons in the cat substantia nigra pars reticulata during drinking. Exp Brain Res 60:375–379
Junquera J, Lanzagorta-Sanchez G, Mejia-Perez BE, Racotta R (1984) Motor activity in decerebrate rats: spontaneous and nutrient-induced changes. Am J Physiol 247:R945–R952
Kessler JP, Jean A (1985) Identification of the medullary swallowing regions in the rat. Exp Brain Res 57:256–263
Kornblith CL, Hall WG (1979) Brain transections selectively alter ingestion and behavioral activation in neonatal rats. J Comp Physiol Psychol 93:1109–1117
Kruger L, Michel F (1962) A single neuron analysis of buccal cavity representation in the sensory trigeminal complex of the cat. Arch Oral Biol 7:491–503
Kucharczyk J, Mogenson GJ (1975) Separate lateral hypothalamic pathways for extracellular and intracellular thirst. Am J Physiol 228:295–301
Lovick TA (1972) The behavioural repertoire of precollicular decerebrate rats. J Physiol (Lond) 226:4P–6P
Lund JP (1984) Sensorimotor integration in the control of mastication. In: Klienberg I, Sessle B (eds) Oro-facial pain and neuromuscular dysfunction: mechanisms and clinical correlates, vol 52. Advances in biosciences. Pergamon Press, Oxford, pp 51–65
Luschei ES (1987) Central projections of the mesencephalic nucleus of the fifth nerve: an autoradiographic study. J Comp Neurol 263:137–145
Malmo RB (1976) Osmosensitive neurons in the rat’s dorsal midbrain. Brain Res 105:105–120
Mark GP, Scott TR, Chang F-C T, Grill HJ (1988) Taste responses in the nucleus tractus solitarius of the chronic decerebrate rat. Brain Res 443:137–148
Mason P, Strassman A, Maciewicz R (1985) Is the jaw-opening reflex a valid model of pain. Brain Res Rev 10:137–146
McNamara JA Jr, Moyers RE (1973) Electromyography of the oral phase of deglutition in the rhesus monkey (Macaca mulatta). Arch Oral Biol 18:995–1002
Miller AJ (1982) Deglutition. Physiol Rev 62:129–184
Moriyama Y (1987) Rhythmical jaw movements and lateral pontomedullary reticular neurons in rats. Comp Biochem Physiol 86A:7–14
Nakamura Y, Kubo Y (1978) Masticatory rhythm in intracellular potential of trigeminal motoneurons induced by stimulation of orbital cortex and amygdala in cats. Brain Res 148:504–509
Norgren R (1978) Projections from the nucleus of the solitary tract in the rat. Neuroscience 3:207–218
Norgren R (1985) Taste and the autonomic nervous system. Chem Senses 10:143–161
Norgren R, Leonard CM (1973) Ascending central gustatory pathways. J Comp Neurol 150:217–238
Nozaki S, Enomoto S, Nakamura Y (1983) Identification and input-output properties of bulbar reticular neurons involved in the cerebral cortical control of trigeminal motoneurons in cats. Exp Brain Res 49:363–372
Nozaki S, Iriki A, Nakamura Y (1986a) Localization of central rhythm generator involved in cortically induced rhythmical masticatory jaw-opening movement in the guinea pig. J Neurophysiol 55:806–825
Nozaki S, Iriki A, Nakamura Y (1986b) Role of corticobulbar projection neurons in cortically induced rhythmical masticatory jaw-opening in the guinea pig. J Neurophysiol 55:826–845
Ogawa H, Hayama T, Yamashita Y (1988) Thermal sensitivity of neurons in a rostral part of the rat solitary tract nucleus. Brain Res 454:321–331
Olsson KA, Sasamoto K, Lund JP (1986) Modulation of transmission in rostral trigeminal sensory nuclei during chewing. J Neurophysiol 55:56–75
Saper CB, Loewy AD (1980) Efferent connections of the parabrachial nucleus in the rat. Brain Res 197:291–317
Scheibel ME, Scheibel AB (1958) Structural substrates for integrative patterns in the brain stem reticular core. In: Jasper HH et al. (eds) Reticular formation of the brain. Little Brown, Boston, pp 31–55
Schneider JS (1986) Interactions between the basal ganglia, the pontine parabrachial region, and the trigeminal system in cats. Neuroscience 19:411–425
Schneider JS, Manettto C, Lidsky TI (1985) Substantia nigra projection to medullary reticular formation: relevance to oculomotor and related motor functions in the cat. Neurosci Lett 62:1–6
Scott TR, Yaxley S, Sienkiewicz ZJ, Rolls ET (1986) Gustatory responses in the nucleus tractus solitarius of the alert cynomologous monkey. J Neurophysiol 55:182–200
Sessle BJ, Greenwood LF (1976) Inputs to trigeminal brain stem neurons from facial, oral, tooth pulp and pharyngolaryngeal tissues: I responses to innocuous and noxious stimuli. Brain Res 117:211–226
Steiner JE (1973) The gustofacial response: observation on normal and anencephalic newborn infants. In: Bosma JF (ed) Oral sensation and perception: development in the fetus and infant. US Department of Health, Education and Welfare, Bethesda, pp 254–278
Storey AT (1968) A functional analysis of sensory units innervating epiglottis and larynx. Exp Neurol 20:366–383
Sumi T (1970) Activity in single hypoglossal fibers during cortically induced swallowing and chewing in rabbits. Pflügers Arch 314:329–346
Suzuki SS, Siegel JM (1985) Reticular formation neurons related to tongue movement in the behaving cat. Exp Neurol 89:689–697
Swanson LW, Sharpe LG (1973) Centrally induced drinking: comparison of angiotensin II- and carbachol-sensitive sites in rats. Am J Physiol 225:566–573
Swanson LW, Kucharczyk J, Mogenson GJ (1978) Autoradiographic evidence for pathways from the medial preoptic area to the midbrain involved in the drinking response to angiotensin II. J Comp Neurol 178:645–660
Sweazey RD, Bradley RM (1987) Responses of lamb spinal trigeminal nucleus neurons to mechanical, thermal and chemical stimulations of the oral cavity and epiglottis. Soc Neurosci Abstr p 779
Sweazey RD, Bradley RM (1988) Responses of lamb nucleus of the solitary tract neurons to chemical stimulation of the epiglottis. Brain Res 439:195–210
Sweazey RD, Bradley RM (1989) Responses of neurons in the lamb nucleus tractus solitarius to stimulation of the caudal oral cavity and epiglottis with different stimulus modalities. Brain Res 480:133–150
Tal M (1987) Neural basis for initiation of rhythmic digastric activity upon midbrain stimulation in the guinea pig. Brain Res 411:58–64
Thexton AJ, Crompton AW (1989) Effect of sensory input from the tongue on jaw movement in normal feeding opossum. J Exp Zool 250:233–243
Thexton AJ, Griffiths C (1979) Reflex oral activity in decerebrate rats of different age. Brain Res 175:1–9
Thexton AJ, McGarrick J (1987) Effect of experimentally elicited rhythmic oral activity on the linguodigastric reflex in the lightly anesthetized rabbit. Exp Neurol 96:104–117
Travers JB (1988) Efferent projections from the anterior nucleus of the solitary tract of the hamster. Brain Res 457:1–11
Travers JB (1989) Hypoglossal unit activity during licking and swallowing. J Dent Res 68:309
Travers JB, Jackson LM (1989) The effects of gustatory stimulation on neurons in and adjacent to the hypoglossal nucleus. Chem Senses 14:756
Travers JB, Norgren R (1983) Afferent projections to the oral motor nuclei in the rat. J Comp Neurol 220:280–298
Travers JB, Norgren R (1986) Electromyographic analysis of the ingestion and rejection of sapid stimuli in the rat. Behav Neurosci 100:544–555
Travers SP, Norgren R (1988) Oral sensory responses in the nucleus of the solitary tract. Soc Neurosci Abstr p 1185
Travers SP, Pfaffmann C, Norgren R (1986) Convergence of lingual and palatal gustatory neural activity in the nucleus of the solitary tract. Brain Res 365:305–320
Travers JB, Waltzer R, Travers S (1988) Sensory-motor mapping of the solitary nucleus and adjacent structures. Chem Senses 13:741
Van Willigen JD, Weijs-Boot J (1984) Phasic and rhythmic responses of the oral musculature to mechanical stimulation of the rat palate. Arch Oral Biol 29:7–11
White NM (1986) Control of sensorimotor functions by dopaminergic nigrostriatal neurons: influence on eating and drinking. Neurosci Biobehav Rev 10:15–36
Whitehead MC (1988) Neuronal architecture of the nucleus of the solitary tract in the hamster. J Comp Neurol 276:547–572
Whitehead MC, Savoy LD (1987) The solitary nucleus of the hamster. Ann N Y Acad Sci 510:707–709
Woods, JW (1964) Behavior of chronic decerebrate rats. J Neurophysiol 27:635–644
Zeigler HP, Jacquin MF, Miller MG (1985) Trigeminal orosensation and ingestive behavior in the rat. Prog Psychobiol Physiol Psychol 11:63–195
Zhang G, Sasamoto K (1990) Projections of two separate cortical areas for rhythmical jaw movements in the rat. Brain Res Bull 24:221–230
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Travers, J.B. (1991). Drinking: Hindbrain Sensorimotor Neural Organization. In: Ramsay, D.J., Booth, D. (eds) Thirst. ILSI Human Nutrition Reviews. Springer, London. https://doi.org/10.1007/978-1-4471-1817-6_16
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DOI: https://doi.org/10.1007/978-1-4471-1817-6_16
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