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Fallopian Tube and Peritoneum

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Diagnostic Pathology of Ovarian Tumors

Abstract

This chapter guides the reader in the classification of tumors of the fallopian tube and peritoneum. Readers will learn methods of defining primary tubal cancer (traditional and newly proposed methods), and tubal cancer’s clinical features, microscopic features, precursors, differential diagnoses, and staging. The second part of the chapter discusses peritoneal carcinoma: its features, diagnostic criteria, and differential diagnoses.

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References

  1. Tavassoli FA, Devilee P, editors. Tumours of the breast and female genital organs. Lyon: IARC; 2003.

    Google Scholar 

  2. Olivier RI, van Beurden M, Lubsen MA, Rookus MA, Mooij TM, van de Vijver MJ, et al. Clinical outcome of prophylactic oophorectomy in BRCA1/BRCA2 mutation carriers and events during follow-up. Br J Cancer. 2004;90(8):1492–7.

    Article  PubMed  CAS  Google Scholar 

  3. Lu KH, Garber JE, Cramer DW, Welch WR, Niloff J, Schrag D, et al. Occult ovarian tumors in women with BRCA1 or BRCA2 mutations undergoing prophylactic oophorectomy. J Clin Oncol. 2000;18(14):2728–32.

    PubMed  CAS  Google Scholar 

  4. Leeper K, Garcia R, Swisher E, Goff B, Greer B, Paley P. Pathologic findings in prophylactic oophorectomy specimens in high-risk women. Gynecol Oncol. 2002;87(1):52–6.

    Article  PubMed  Google Scholar 

  5. Powell CB, Kenley E, Chen LM, Crawford B, McLennan J, Zaloudek C, et al. Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancy. J Clin Oncol. 2005;23(1):127–32.

    Article  PubMed  Google Scholar 

  6. Carcangiu ML, Peissel B, Pasini B, Spatti G, Radice P, Manoukian S. Incidental carcinomas in prophylactic specimens in BRCA1 and BRCA2 germ-line mutation carriers, with emphasis on fallopian tube lesions: report of 6 cases and review of the literature. Am J Surg Pathol. 2006;30(10):1222–30.

    Article  PubMed  Google Scholar 

  7. Shaw PA, Rouzbahman M, Pizer ES, Pintilie M, Begley H. Candidate serous cancer precursors in fallopian tube epithelium of BRCA1/2 mutation carriers. Mod Pathol. 2009;22(9):1133–8.

    Article  PubMed  CAS  Google Scholar 

  8. Lamb JD, Garcia RL, Goff BA, Paley PJ, Swisher EM. Predictors of occult neoplasia in women undergoing risk-reducing salpingo-oophorectomy. Am J Obstet Gynecol. 2006;194(6):1702–9.

    Article  PubMed  Google Scholar 

  9. Hirst JE, Gard GB, McIllroy K, Nevell D, Field M. High rates of occult fallopian tube cancer diagnosed at prophylactic bilateral salpingo-oophorectomy. Int J Gynecol Cancer. 2009;19(5):826–9.

    Article  PubMed  Google Scholar 

  10. Rebbeck TR, Lynch HT, Neuhausen SL, Narod SA, Van’t Veer L, Garber JE, et al. Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations. N Engl J Med. 2002;346(21):1616–22.

    Article  PubMed  Google Scholar 

  11. Lu KH, Bell DA, Welch WR, Berkowitz RS, Mok SC. Evidence for the multifocal origin of bilateral and advanced human serous borderline ovarian tumors. Cancer Res. 1998;58(11):2328–30.

    PubMed  CAS  Google Scholar 

  12. Kindelberger DW, Lee Y, Miron A, Hirsch MS, Feltmate C, Medeiros F, et al. Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship. Am J Surg Pathol. 2007;31(2):161–9.

    Article  PubMed  Google Scholar 

  13. Longacre TA, Oliva E, Soslow RA. Recommendations for the reporting of fallopian tube neoplasms. Hum Pathol. 2007;38(8):1160–3.

    Article  PubMed  Google Scholar 

  14. Medeiros F, Muto MG, Lee Y, Elvin JA, Callahan MJ, Feltmate C, et al. The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol. 2006;30(2):230–6.

    Article  PubMed  Google Scholar 

  15. Quddus MR, Sung CJ, Lauchlan SC. Benign and malignant serous and endometrioid epithelium in the omentum. Gynecol Oncol. 1999;75(2):227–32.

    Article  PubMed  CAS  Google Scholar 

  16. Weir MM, Bell DA, Young RH. Grade 1 peritoneal serous carcinomas: a report of 14 cases and comparison with 7 peritoneal serous psammocarcinomas and 19 peritoneal serous borderline tumors. Am J Surg Pathol. 1998;22(7):849–62.

    Article  PubMed  CAS  Google Scholar 

  17. Hu CY, Taymor ML, Hertig AT. Primary carcinoma of the fallopian tube. Am J Obstet Gynecol. 1950;59(1):58–67.

    PubMed  CAS  Google Scholar 

  18. Jarboe E, Folkins A, Nucci MR, Kindelberger D, Drapkin R, Miron A, et al. Serous carcinogenesis in the fallopian tube: a descriptive classification. Int J Gynecol Pathol. 2008;27(1):1–9.

    Article  PubMed  Google Scholar 

  19. Folkins AK, Jarboe EA, Saleemuddin A, Lee Y, Callahan MJ, Drapkin R, et al. A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations. Gynecol Oncol. 2008;109(2):168–73.

    Article  PubMed  CAS  Google Scholar 

  20. Vang R, Shih Ie M, Kurman RJ. Ovarian low-grade and high-grade serous carcinoma: pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems. Adv Anat Pathol. 2009;16(5):267–82.

    Article  PubMed  Google Scholar 

  21. Dehari R, Kurman RJ, Logani S, Shih Ie M. The development of high-grade serous carcinoma from atypical proliferative (borderline) serous tumors and low-grade micropapillary serous carcinoma: a morphologic and molecular genetic analysis. Am J Surg Pathol. 2007;31(7):1007–12.

    Article  PubMed  Google Scholar 

  22. Jarboe EA, Miron A, Carlson JW, Hirsch MS, Kindelberger D, Mutter GL, et al. Coexisting intraepithelial serous carcinomas of the endometrium and fallopian tube: frequency and potential significance. Int J Gynecol Pathol. 2009;28(4):308–15.

    Article  PubMed  Google Scholar 

  23. Crum CP. Intercepting pelvic cancer in the distal fallopian tube: theories and realities. Mol Oncol. 2009;3(2):165–70.

    Article  PubMed  CAS  Google Scholar 

  24. Nordin AJ. Primary carcinoma of the fallopian tube: a 20-year literature review. Obstet Gynecol Surv. 1994;49(5):349–61.

    Article  PubMed  CAS  Google Scholar 

  25. Colgan TJ, Murphy J, Cole DE, Narod S, Rosen B. Occult carcinoma in prophylactic oophorectomy specimens: prevalence and association with BRCA germline mutation status. Am J Surg Pathol. 2001;25(10):1283–9.

    Article  PubMed  CAS  Google Scholar 

  26. Edge S, Byrd D, Compton C, Fritz A, Greene F, Trotti A, editors. American joint committee on cancer: cancer staging, handbook/cervix uteri. 7th ed. New York: Springer; 2010.

    Google Scholar 

  27. Colgan TJ. Challenges in the early diagnosis and staging of fallopian-tube carcinomas associated with BRCA mutations. Int J Gynecol Pathol. 2003;22(2):109–20.

    Article  PubMed  Google Scholar 

  28. Alvarado-Cabrero I, Navani SS, Young RG, Scully RE. Tumor of the fimbriated end of the fallopian tube: a clinicopathologic analysis of 20 cases, including nine carcinomas. Int J Gynecol Pathol. 1997;16:189–96.

    Article  PubMed  CAS  Google Scholar 

  29. Alvarado-Cabrero I, Young RH, Vamvakas EC, Scully RE. Carcinoma of the fallopian tube: a clinicopathologic study of 105 cases with observations on staging and prognostic factors. Gynecol Oncol. 1999;72:367–79.

    Article  PubMed  CAS  Google Scholar 

  30. Chu PG, Weiss LM. Expression of cytokeratin 5/6 in epithelial neoplasms: an immunohistochemical study of 509 cases. Mod Pathol. 2002;15(1):6–10.

    Article  PubMed  Google Scholar 

  31. Ordonez NG. Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas. Am J Surg Pathol. 1998;22(10):1203–14.

    Article  PubMed  CAS  Google Scholar 

  32. Nascimento AG, Keeney GL, Fletcher CD. Deciduoid peritoneal mesothelioma. An unusual phenotype affecting young females. Am J Surg Pathol. 1994;18(5):439–45.

    Article  PubMed  CAS  Google Scholar 

  33. Shanks JH, Harris M, Banerjee SS, Eyden BP, Joglekar VM, Nicol A, et al. Mesotheliomas with deciduoid morphology: a morphologic spectrum and a variant not confined to young females. Am J Surg Pathol. 2000;24(2):285–94.

    Article  PubMed  CAS  Google Scholar 

  34. Funk KC, Heiken JP. Papillary cystadenoma of the broad ligament in a patient with von Hippel-Lindau disease. AJR Am J Roentgenol. 1989;153(3):527–8.

    PubMed  CAS  Google Scholar 

  35. Gaffey MJ, Mills SE, Boyd JC. Aggressive papillary tumor of middle ear/temporal bone and adnexal papillary cystadenoma. Manifestations of von Hippel-Lindau disease. Am J Surg Pathol. 1994;18(12):1254–60.

    Article  PubMed  CAS  Google Scholar 

  36. Gersell DJ, King TC. Papillary cystadenoma of the mesosalpinx in von Hippel-Lindau disease. Am J Surg Pathol. 1988;12(2):145–9.

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Pathology and Laboratory Medicine, Mount Sinai Hospital, 600 University Avenue, Toronto, ON, M5G 1X5, Canada

    Terence J. Colgan M.D.

  2. Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada

    Martin C. Chang M.D., Ph.D.

Authors
  1. Terence J. Colgan M.D.
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  2. Martin C. Chang M.D., Ph.D.
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Editor information

Editors and Affiliations

  1. Dept. Pathology, Memorial Sloan-Kettering Cancer Center, York Ave. 1275, NEW YORK, 10021, New York, USA

    Robert A. Soslow

  2. SUNY Stony Brook, Department of Pathology, Stony Brook Univ Medical Center, Hospital Level 2, Room 766, Stony Brook, 11794-7025, New York, USA

    Carmen Tornos

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Colgan, T.J., Chang, M.C. (2011). Fallopian Tube and Peritoneum. In: Soslow, R., Tornos, C. (eds) Diagnostic Pathology of Ovarian Tumors. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9751-7_17

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  • DOI: https://doi.org/10.1007/978-1-4419-9751-7_17

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-9750-0

  • Online ISBN: 978-1-4419-9751-7

  • eBook Packages: MedicineMedicine (R0)

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