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Pharmacological Applications of Biocompatible Carbon Nanotubes and Their Emerging Toxicology Issues

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Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes

Part of the book series: Carbon Materials: Chemistry and Physics ((CMCP,volume 1))

Abstract

Since their discovery in 1991, carbon nanotubes (CNTs) have been studied for their application as diagnostic tools, chemical sensors, and vectors for drug delivery. Carbon nanotubes are of great interest because of their unique array of physical and chemical properties, including their high aspect ratio, ultralight weight, high mechanical strength, high electrical conductivity, high thermal conductivity, and high surface area. The unique properties of carbon nanotubes also raise substantial concern about their potentially toxic effects on the environment and human health. This review focuses on the current pharmacological applications and emerging toxicology issues of biocompatible carbon nanotubes. Carbon nanotubes as agents for drug delivery, cancer therapeutics, along with their in vivo challenges and potential toxicity are discussed.

In Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes, Franco Cataldo and Tatiana Da Ros (eds.), Springer Vol. 1, Topics in Carbon Materials Chemistry and Physics, 2007.

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Authors and Affiliations

  1. Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies Rensselaer Polytechnic Institute, Biotech Center 4005, 110 8th Street, Troy, NY, 12180-3590, USA

    Tae-Joon Park & Robert J. Linhardt

  2. Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies Rensselaer Polytechnic Institute, Biotech Center 4005, 110 8th Street, Troy, NY, 12180-3590, USA

    Jeffrey G. Martin & Robert J. Linhardt

  3. Department of Biology, Center for Biotechnology and Interdisciplinary Studies Rensselaer Polytechnic Institute, Biotech Center 4005, 110 8th Street, Troy, NY, 12180-3590, USA

    Jeffrey G. Martin & Robert J. Linhardt

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  1. Tae-Joon Park
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  1. Lupi Chemical Research Institute, Via Casilina 1626/A, 00133, Rome, Italy

    Franco Cataldo (Director) (Director)

  2. Dipartimento di Scienze Farmaceutiche, University of Trieste, Piazzale Europe, I-34127, Trieste, Italy

    Tatiana Da Ros

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Park, TJ., Martin, J.G., Linhardt, R.J. (2008). Pharmacological Applications of Biocompatible Carbon Nanotubes and Their Emerging Toxicology Issues. In: Cataldo, F., Da Ros, T. (eds) Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes. Carbon Materials: Chemistry and Physics, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6845-4_12

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