Abstract
Active agents are only useful for therapy when they are delivered to their cellular and molecular site of action. The delivery agent thus goes hand in hand with the active agent to produce the therapeutic system. There is now a bewildering collection of technology available, from programmed infusion pumps at the bioengineering end of the spectrum to complex coated ion-exchange beads at the other. This chapter will illustrate some of the principles of systems devised at Strathclyde University which, in some cases, have been evaluated in clinical situations. These will illustrate how sustained delivery and constant delivery can be obtained over short or long periods by very practical technology.
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Active agents are only useful for therapy when they are delivered to their cellular and molecular site of action. The delivery agent thus goes hand in hand with the active agent to produce the therapeutic system. There is now a bewildering collection of technology available, from programmed infusion pumps at the bioengineering end of the spectrum to complex coated ion-exchange beads at the other. This chapter will illustrate some of the principles of systems devised at Strathclyde University which, in some cases, have been evaluated in clinical situations. These will illustrate how sustained delivery and constant delivery can be obtained over short or long periods by very practical technology.
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Rashid, A. (1980). Some aspects of surface chemistry, microencapsulation and in-vitro evaluation of ß-estradiol from an injectable formulation. M.Sc. Thesis, University of Strathclyde, Glasgow.
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© 1988 Bioengineering Unit, University of Strathclyde
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Graham, N.B. (1988). Sustained and Programmed Delivery of Active Agents. In: Paul, J.P., McCruden, A.B., Schuetz, P.W. (eds) The Influence of New Technology on Medical Practice. Keynes Seminars. Palgrave, London. https://doi.org/10.1007/978-1-349-09609-1_35
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DOI: https://doi.org/10.1007/978-1-349-09609-1_35
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