Abstract
Lung cancer is the leading cause of cancer death in the world; over 1.2 million new cases and 1.1 million worldwide deaths were predicted for 2004.1 These statistics are astounding given the rarity of lung cancer during the first half of the 20th century, when lung cancer had a lower incidence than liver, prostate, colon, stomach, uterine, breast, and even ovarian cancer. Only a sound understanding of the complex epidemiologic, etiologic, and clinicopathologic aspects of lung carcinoma will enable clinical and scientific progress against this deadly disease regardless of technological advances. Recent modifications in the World Health Organization (WHO) classification of non-small-cell lung cancer (NSCLC) reflect our greater understanding of lung cancer pathology. This chapter provides the necessary information for sound pathologic diagnoses by reviewing general aspects of lung carcinoma as well as the clinicopathologic features of the most common types of NSCLC, namely squamous cell carcinoma (SCC), adenocarcinoma, large cell carcinoma (LCC), and their variants.
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Flieder, D.B., Hammar, S.P. (2008). Common Non-Small-Cell Carcinomas and Their Variants. In: Tomashefski, J.F., Cagle, P.T., Farver, C.F., Fraire, A.E. (eds) Dail and Hammar’s Pulmonary Pathology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-72114-9_4
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