Abstract
It has been a long path for particulate systems in biomedical applications. Since long time ago that these micron and nanosize systems synthesised from the most varied materials find application in the biomaterials field, mainly as drug delivery carrier systems. The aim of drug delivery systems is to facilitate the dosage and duration of the drug effect, causing the minimal harm to the patient and improving human health1,2. Typically, they allow for the reduction of the dosage frequency3 and are non-toxic4. Back in time, these systems designed for the controlled delivery of drugs were found extremely promising for several applications, such as the delivery of insulin5–8, contraceptives9–12, cancer therapeutics13–16 among others17.
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Silva, G.A., Costa, F.J., Neves, N.M., Reis, R.L. (2004). Microparticulate Release Systems Based on Natural Origin Materials. In: Hasirci, N., Hasirci, V. (eds) Biomaterials. Advances in Experimental Medicine and Biology, vol 553. Springer, Boston, MA. https://doi.org/10.1007/978-0-306-48584-8_22
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