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Advancements in Spine FE Mesh Development: Toward Patient-Specific Models

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Patient-Specific Modeling in Tomorrow's Medicine

Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials ((SMTEB,volume 09))

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Abstract

Laboratory-driven experimental studies are capable of delineating the biomechanical characteristics of the spine. They are limited, however, to external responses; that is, internal stresses and strains throughout the structures are not readily attained. Mathematical simulations provide a unique opportunity to serve as an adjunct to experimental studies to predict the external responses, while complementing the experiments by providing such internal responses. Musculoskeletal finite element (FE) analyses have emerged as an invaluable tool in orthopaedic-related research. While it has provided significant insight into the biomechanics of the spine, the demands associated with modeling the geometrically complex structures often limit its utility. Individualized models are important for future development of this field, as they offer a means of correlating mechanical predictions with clinical outcomes. However, relatively few FE studies to date have employed specimen- or patient-specific models. Spine modeling is by no means an exception. In this chapter we describe multiblock methods for generating subject-specific spine meshes to alleviate the current limitations of spine meshing. In addition, we demonstrate additional computational tools to perform “virtual surgery,” and show examples of how the techniques have been applied to date.

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Abbreviations

FE:

Finite element

ACDF:

Anterior cervical discectomy and fusion

FSU:

Functional spinal unit

CT:

Computed tomography

MR:

Magnetic resonance

IVD:

Intervertebral disc

ALL:

Anterior longitudinal ligament

PLL:

Posterior longitudinal ligament

CL:

Capsular ligament

LF:

Ligamentum flavum

IS:

Interspinous ligament

ODL:

Open door laminoplasty

DDL:

Double door laminoplasty

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Authors and Affiliations

  1. Department of Biomedical Engineering, The University of Iowa, Iowa City, IA, USA

    Nicole A. Kallemeyn, Kiran H. Shivanna, Nicole A. DeVries, Swathi Kode, Anup A. Gandhi & Nicole M. Grosland

  2. Center for Computer Aided Design, The University of Iowa, Iowa City, IA, USA

    Nicole A. Kallemeyn, Kiran H. Shivanna, Nicole A. DeVries, Swathi Kode, Anup A. Gandhi & Nicole M. Grosland

  3. Department of Orthopaedics and Rehabilitation, The University of Iowa, Iowa City, IA, USA

    Douglas C. Fredericks, Joseph D. Smucker & Nicole M. Grosland

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  1. Nicole A. Kallemeyn
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  1. Fac. Engineering, Dept. Biomedical Engineering, Tel Aviv University, Ramat Aviv, 69978, Israel

    Amit Gefen

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Kallemeyn, N.A. et al. (2011). Advancements in Spine FE Mesh Development: Toward Patient-Specific Models. In: Gefen, A. (eds) Patient-Specific Modeling in Tomorrow's Medicine. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 09. Springer, Berlin, Heidelberg. https://doi.org/10.1007/8415_2011_93

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  • DOI: https://doi.org/10.1007/8415_2011_93

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