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Patient-Specific Modeling of the Cornea

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Patient-Specific Modeling in Tomorrow's Medicine

Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials ((SMTEB,volume 09))

Abstract

This chapter reviews the up-to-date literature in regard to patient-specific modeling of the human cornea. First, the relevant anatomical, morphological and physiological aspects are summarized. Then, examples of non-patient-specific seldom are addressed before existing patient-specific models are discussed. Finally, an overview is presented, of the development of a patient-specific model that can aid the clinician to prognose response to different intraocular pressure controlling medications. This feature can be very useful in cases of keratoconus—a disease of the cornea which involves changes to the corneal microstructure as well as to its macrostructure, gradually causing a conic-like corneal shape that distorts vision.

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Acknowledgment

The authors wish to acknowledge the help of Sharon Sherry for the technical editing of this chapter.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, 69978, Tel Aviv, Israel

    Roy Asher & Amit Gefen

  2. Cornea and External Disease, Department of Ophthalmology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, 69978, Tel Aviv, Israel

    David Varssano

Authors
  1. Roy Asher
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  2. Amit Gefen
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  3. David Varssano
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Corresponding author

Correspondence to Roy Asher .

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Editors and Affiliations

  1. Fac. Engineering, Dept. Biomedical Engineering, Tel Aviv University, Ramat Aviv, 69978, Israel

    Amit Gefen

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Asher, R., Gefen, A., Varssano, D. (2011). Patient-Specific Modeling of the Cornea. In: Gefen, A. (eds) Patient-Specific Modeling in Tomorrow's Medicine. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 09. Springer, Berlin, Heidelberg. https://doi.org/10.1007/8415_2011_106

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  • DOI: https://doi.org/10.1007/8415_2011_106

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-24617-3

  • Online ISBN: 978-3-642-24618-0

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