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Personalized Medicine: Where Do We Go from Here?

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Personalized Medicine with a Nanochemistry Twist

Part of the book series: Topics in Medicinal Chemistry ((TMC,volume 20))

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Abstract

The past decade has seen a surplus of nanotechnology-based methodologies for “theranostic” application, sensors, and real-time monitoring of biological events, therapy, and image-guided precision drug delivery. While nanotechnology offers great promise to address some of the critical clinical challenges, the future of this technology toward personalized medicine will largely be predisposed by design principles for developing translatable, “safer” nanoplatforms in concert with imaging agents, therapy, and homing ligands.

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Abbreviations

ECM:

Extracellular matrix

ENM:

Engineered nanomaterial

EPR:

Enhanced permeability retention

I.V.:

Intravenous

MPS:

Mononuclear phagocyte system

MS:

Mass spectrometry

NIPAM:

N-Isopropylacrylamide

NLS:

Nuclear localization signal

NMR:

Nuclear magnetic resonance

NP:

Nanoparticle(s)

PC:

Protein corona

PEG:

Polyethylene glycol

PS:

Polystyrene

RES:

Reticuloendothelial system

SWCNT:

Single-walled carbon nanotubes

Tf:

Transferrin

TfR:

Transferrin receptor

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Authors and Affiliations

  1. Department of Bioengineering, University of Illinois at Urbana Champaign, Urbana, IL, USA

    Dipanjan Pan

  2. Beckman Institute for Science and Technology, Urbana, IL, USA

    Dipanjan Pan

  3. Department of Materials Science and Engineering, University of Illinois at Urbana Champaign, Urbana, IL, USA

    Dipanjan Pan

  4. Carle Foundation Hospital, Urbana, IL, USA

    Dipanjan Pan

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  1. Dipanjan Pan
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Correspondence to Dipanjan Pan .

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Editors and Affiliations

  1. Department of Bioengineering, University of Illinois at Urbana Champain, Urbana, Illinois, USA

    Dipanjan Pan

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Pan, D. (2015). Personalized Medicine: Where Do We Go from Here?. In: Pan, D. (eds) Personalized Medicine with a Nanochemistry Twist. Topics in Medicinal Chemistry, vol 20. Springer, Cham. https://doi.org/10.1007/7355_2015_95

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