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Flavonoids in Sophora Species

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Bioactive Heterocycles VII

Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 16))

Abstract

Sophora species of Leguminosae are abundantly present in the natural kingdom. Today, among Sophora plants, the flavonoids of the plant phenols occupy a remarkable position. For a very long time flavonoids have been used as natural pigments and dyes. Some of the colorful anthocyanins of the glucosides are used for color and flavor in foodstuffs. Therefore, these flavonoids are beneficial to daily human life. Herein we concentrate on flavonoids in Sophora plants, and the relationship between their chemical structures and nutraceutical effect. For this purpose, soy-based infant formulas, osteoporosis, antitumor activity, antimicrobial activity, anti-HIV activity, radical generation and O2 – scavenging activity, and enzyme inhibitory activity have been described.

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References

  1. Zhang L, Xu L, Xiao SS, Liao QF, Li Q, Liang J, Chen XH, Bi KS (2007) J Pharm Biomed Anal 44:1019

    Article  CAS  Google Scholar 

  2. Song T, Barua K, Buseman G, Murphy PA (1998) Am J Clin Nutr 68(6 Suppl):1474S

    CAS  Google Scholar 

  3. Setchell KD, Zimmer-Nechemias L, Cai J, Heubi JE (1997) Lancet 350(9070):23

    Article  CAS  Google Scholar 

  4. Setchell KD, Zimmer-Nechemias L, Cai J, Heubi JE (1998) Am J Clin Nutr 68(6 Suppl):1453S

    CAS  Google Scholar 

  5. Song WO, Chun OK, Hwang I, Shin HS, Kim BG, Kim KS, Lee SY, Shin D, Lee SG (2007) J Med Food 10:571

    Article  CAS  Google Scholar 

  6. Liu IM, Sheu SJ (1989) Am J Chin Med 17:179

    Article  CAS  Google Scholar 

  7. Min B, Oh SR, Lee HK, Takatsu K, Chang IM, Min KR, Kim Y (1999) Planta Med 65:408

    Article  CAS  Google Scholar 

  8. Tang Y, Lou F, Wang J, Zhuang S (2001) J Nat Prod 64:1107

    Article  CAS  Google Scholar 

  9. Park JA, Kim HJ, Jin C, Lee KT, Lee YS (2003) Arch Pharm Res 26:1009

    Article  CAS  Google Scholar 

  10. Hillerns PI, Wink M (2005) Planta Med 71:1065

    Article  CAS  Google Scholar 

  11. Joo SS, Kang HC, Lee MW, Choi YW, Lee DI (2003) Arch Pharm Res 26:1029

    Article  CAS  Google Scholar 

  12. Shirataki Y, Yokoe I, Noguchi M, Tomimori T, Komatsu M (1988) Chem Pharm Bull 36:2220

    CAS  Google Scholar 

  13. Kang TH, Jeong SJ, Ko WG, Kim NY, Lee BH (2000) J Nat Prod 63:680

    Article  CAS  Google Scholar 

  14. Shirataki Y, Motohashi N, Tani S, Sakagami H, Satoh K, Nakashima H, Mahapatra SK, Ganguly K, Dastidar SG, Chakrabarty AN (2001) Anticancer Res 21:275

    CAS  Google Scholar 

  15. Shirataki Y, Tani S, Sakagami H, Satoh K, Nakashima H, Gotoh K, Motohashi N (2001) Anticancer Res 21:2643

    CAS  Google Scholar 

  16. Shirataki Y, Wakae M, Yamamoto Y, Hashimoto K, Satoh K, Ishihara M, Kikuchi H, Nishikawa H, Minagawa K, Motohashi N, Sakagami H (2004) Anticancer Res 24:1481

    CAS  Google Scholar 

  17. Quan W, Lee HJ, Kim CY, Noh CW, Um BH, Oak MH, Kim KM (2008) Planta Med 74:168

    Article  CAS  Google Scholar 

  18. De Naeyer A, Vanden Berghe W, Pocock V, Milligan S, Haegeman G, De Keukeleire D (2004) J Nat Prod 67:1829

    Article  Google Scholar 

  19. Shen CC, Lin TW, Huang YL, Wan ST, Shien BJ, Chen CC (2006) J Nat Prod 69:1237

    Article  CAS  Google Scholar 

  20. Chowdhury SA, Kishino K, Satoh R, Hashimoto K, Kikuchi H, Nishikawa H, Shirataki Y, Sakagami H (2005) Anticancer Res 25:2055

    CAS  Google Scholar 

  21. Bobrowska-Hägerstrand M, Lillås M, Mrówczyñska L, Wróbel A, Shirataki Y, Motohashi N, Hägerstrand H (2006) Anticancer Res 26:2081

    Google Scholar 

  22. Woo ER, Kwak JH, Kim HJ, Park H (1998) J Nat Prod 61:1552

    Article  CAS  Google Scholar 

  23. Dastidar SG, Manna A, Kumar KA, Mazumdar K, Dutta NK, Chakrabarty AN, Motohashi N, Shirataki Y (2004) Int J Antimicrob Agents 23:99

    Article  CAS  Google Scholar 

  24. Cha JD, Jeong MR, Jeong SI, Lee KY (2007) J Microbiol Biotechnol 17:858

    CAS  Google Scholar 

  25. Jung HJ, Kang SS, Woo JJ, Choi JS (2005) Arch Pharm Res 28:1333

    Article  CAS  Google Scholar 

  26. Jung HJ, Kang SS, Hyun SK, Choi JS (2005) Arch Pharm Res 28:534

    Article  CAS  Google Scholar 

  27. Piao XL, Piao XS, Kim SW, Park JH, Kim HY, Cai SQ (2006) Biol Pharm Bull 29:1911

    Article  CAS  Google Scholar 

  28. Jung HA, Jeong DM, Chung HY, Lim HA, Kim JY, Yoon NY, Choi JS (2008) Biol Pharm Bull 31:908

    Article  CAS  Google Scholar 

  29. Shin HJ, Kim HJ, Kwak JH, Chun HO, Kim JH, Park H, Kim DH, Lee YS (2002) Bioorg Med Chem Lett 12:2313

    Article  CAS  Google Scholar 

  30. Lee NK, Son KH, Chang HW, Kang SS, Park H, Heo MY, Kim HP (2004) Arch Pharm Res 27:1132 (structure of sophoflavescenol is not correct)

    Article  CAS  Google Scholar 

  31. Son JK, Park JS, Kim JA, Kim Y, Chung SR, Lee SH (2003) Planta Med 69:559

    Article  CAS  Google Scholar 

  32. Kim SJ, Son KH, Chang HW, Kang SS, Kim HP (2003) Biol Pharm Bull 26:1348

    Article  CAS  Google Scholar 

  33. Chung MY, Rho MC, Ko JS, Ryu SY, Jeune KH, Kim K, Lee HS, Kim YK (2004) Planta Med 70:258

    Article  CAS  Google Scholar 

  34. Hwang JS, Lee SA, Hong SS, Lee KS, Lee MK, Hwang BY, Ro JS (2005) Arch Pharm Res 28:190

    Article  CAS  Google Scholar 

  35. Kim JH, Ryu YB, Kang NS, Lee BW, Heo JS, Jeong IY, Park KH (2006) Biol Pharm Bull 29:302

    Article  CAS  Google Scholar 

  36. Sato S, Takeo J, Aoyama C, Kawahara H (2007) Bioorg Med Chem 15:3445

    Article  CAS  Google Scholar 

  37. Ryu YB, Westwood IM, Kang NS, Kim HY, Kim JH, Moon YH, Park KH (2008) Phytomedicine 15:612

    Article  CAS  Google Scholar 

  38. Hyun SK, Lee WH, Jeong da M, Kim Y, Choi JS (2008) Biol Pharm Bull 31:154

    Article  CAS  Google Scholar 

  39. Jung HA, Yoon NY, Kang SS, Kim YS, Choi JS (2008) J Pharm Pharmacol 60:1227

    Article  CAS  Google Scholar 

  40. Yang HM, Shin HR, Cho SH, Song GY, Lee IJ, Kim MK, Lee SH, Ryu JC, Kim Y, Jung SH (2006) Arch Pharm Res 29:969

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado-shi, 350-0295, Saitama, Japan

    Yoshiaki Shirataki

  2. Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose-shi, 204-8588, Tokyo, Japan

    Noboru Motohashi

Authors
  1. Yoshiaki Shirataki
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  2. Noboru Motohashi
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Correspondence to Yoshiaki Shirataki .

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Noboru Motohashi

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© 2009 Springer-Verlag Berlin Heidelberg

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Shirataki, Y., Motohashi, N. (2009). Flavonoids in Sophora Species. In: Motohashi, N. (eds) Bioactive Heterocycles VII. Topics in Heterocyclic Chemistry, vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7081_2009_128

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