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Supramolecular Host–Guest Chemistry of Heterocyclic V-Shaped Molecules

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Heterocyclic Supramolecules II

Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 18))

Abstract

The host–guest inclusion properties of heterocyclic molecules that utilise C 2-symmetric V-shaped building blocks in their construction are reviewed. Such compounds are classified here according to the molecular structures of these building blocks. Salient features of the crystal structures of the resulting inclusion compounds are described and the f unctions of their key supramolecular synthons are analysed. Concepts underpinning the deliberate design and synthesis of new host molecules of this type are explained and then put into practice.

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Notes

  1. 1.

    In this article, the molecular structure of only one enantiomer of a chiral molecule will be drawn, and the terms syn and anti will refer to the relative geometry of neighbouring bridges present in multicyclic structures.

Abbreviations

EE:

edge-edge

EF:

edge-face

OFF:

offset face-face

PHD:

pi–halogen dimer

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Acknowledgements

I wish to thank Solhe Alshahateet, Jason Ashmore, Chris Marjo and Noman Rahman for their synthetic work, and Don Craig and Marcia Scudder for the crystallographic determinations, described in this article. Financial support of our research was provided by the Australian Research Council and the University of New South Wales. I also gratefully thank Dr. Scudder for generating the crystal structure diagrams used to illustrate this article.

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  1. School of Chemistry, Dalton Building, The University of New South Wales, UNSW Sydney, NSW, 2052, Australia

    Roger Bishop

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  1. Roger Bishop
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Correspondence to Roger Bishop .

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  1. Faculty of Pharmaceutical Sciences, Chiba Institute of Science, Shiomi-Cho 15-8, Chiba, 288-0025, Japan

    Kiyoshi Matsumoto

  2. Graduate School of Science &, University of Toyama, Gofuku 3190, Toyama, 930-8555, Japan

    Naoto Hayashi

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Bishop, R. (2008). Supramolecular Host–Guest Chemistry of Heterocyclic V-Shaped Molecules. In: Matsumoto, K., Hayashi, N. (eds) Heterocyclic Supramolecules II. Topics in Heterocyclic Chemistry, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7081_2008_9

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