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Non-Steroidal Anti-Inflammatory Drugs in Water pp 115–129Cite as

Teratogenesis and Embryotoxicity Induced by Non-steroidal Anti-Inflammatory Drugs in Aquatic Organisms

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Part of the book series: The Handbook of Environmental Chemistry ((HEC,volume 96))

Abstract

The continuous elimination of pharmaceutical products to water sources has become a worldwide problem and has been getting considerable attention due to the effects that this compounds have induced in aquatic organisms, specifically non-steroidal anti-inflammatory drugs (NSAIDs), one of the most representative group of medications and the most consumed around the world, highlighting the teratogenic and embryotoxic effects induced by NSAIDs on early life stages of different organisms being this the most vulnerable stages in development; the main representants of NSAID group (diclofenac, ibuprofen, naproxen, ketoprofen, paracetamol, acetylsalicylic acid) have induced adverse embryonic effects, which can be consider for the development of strategies for an appropriate disposal of pharmaceutical residues, as well as establish maximum permissible limits for its emission to the environment.

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Authors and Affiliations

  1. Laboratorio de Toxicología Ambiental, Facultad de Química, Universidad Autónoma del Estado de México, Toluca, Estado de México, Mexico

    Itzayana Pérez-Alvarez, Hariz Islas-Flores, Leobardo Manuel Gómez-Oliván & Octavio Dublán García

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  1. Itzayana Pérez-Alvarez
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  2. Hariz Islas-Flores
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  3. Leobardo Manuel Gómez-Oliván
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  4. Octavio Dublán García
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Correspondence to Hariz Islas-Flores .

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  1. Environmental Toxicology Lab, Faculty of Chemistry, Autonomous University of the State of Mexico, Toluca, Estado de México, Mexico

    Leobardo Manuel Gómez-Oliván

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Pérez-Alvarez, I., Islas-Flores, H., Gómez-Oliván, L.M., García, O.D. (2020). Teratogenesis and Embryotoxicity Induced by Non-steroidal Anti-Inflammatory Drugs in Aquatic Organisms. In: Gómez-Oliván, L.M. (eds) Non-Steroidal Anti-Inflammatory Drugs in Water. The Handbook of Environmental Chemistry, vol 96. Springer, Cham. https://doi.org/10.1007/698_2020_545

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