Skip to main content

Automatic Detection of Microaneurysms in Color Fundus Images of the Human Retina by Means of the Bounding Box Closing

  • Conference paper
  • First Online:
Medical Data Analysis (ISMDA 2002)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2526))

Included in the following conference series:

Abstract

In this paper we propose a new algorithm for the detection of microaneurysms in color fundus images of the human retina. Microaneurysms are the first unequivocal indication of Diabetic Retinopathy (DR), a severe and wide-spread eye disease. Their automatic detection may play a major role in computer assisted diagnosis of DR. We propose an algorithm that can be divided into four steps. The first step is an image enhancement technique that comprises normalization and noise reduction. The second step ist the extraction of small details that fulfill a certain criterion: This leads to the definition of the bounding box closing. Then, an automatic threshold depending on image quality is calculated. In the last step false positives are eliminated.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. P. Massin, A. Erginay, and A. Gaudric, Rétinopathie Diabéthique, vol. 1, Paris, elsevier edition, 2000.

    Google Scholar 

  2. F. Zana, Une approche morphologique pour les détections et Bayesienne pour le recalage d’images multimodales: Application aux images rétiniennes, thesis, ENSMP, CMM, May 1999.

    Google Scholar 

  3. B. Lay, Analyse automatique des images angiofluorographiques au cours de la rétinopathie diabétique, thesis, ENSMP, CMM, June 1983.

    Google Scholar 

  4. T. Spencer et al., “An image processing strategy for the segmentation and quantification of mycroaneurysms in fluorescein angiograms of the ocular fundus,” Computers and biomedical research, vol. 29, pp. 284–302, 1996.

    Article  Google Scholar 

  5. A. M. MendonÇ et al., “tomatic segmentation of microaneurysms in retinal angiograms of diabetic patients,”proc. ICIAP 99, pp. 728–733, 1999.

    Google Scholar 

  6. A. Frame et al., “A comparison of computer based classification methods applied to the detection of microaneurysms in ophthalmic fluorescein angiograms,” Computers in Biology and Medecine, vol. 28, pp. 225–238, 1998.

    Article  Google Scholar 

  7. T. Hellstedt, E. Vesti, and I. Immonen, “Identification of individual microaneurysms: A comparison between fluorescein angiograms and red-free and colour photographs,” Graefe’s Arch Clin Exp Ophtalmol, vol. 234, pp. 13–17, 1996.

    Article  Google Scholar 

  8. M. J. Cree, J. A. Olson, K. C. McHardy, J. V. Forrester, and P. F. Sharp, “Automated microaneurysm detection,” International Conference on Image Processing (ICIP), sep 1996.

    Google Scholar 

  9. L. Vincent, “Morphological area openings and closings for grayscale images,” Shape in picture, NATO workshop, Driebergen, Sep 1992.

    Google Scholar 

  10. P. Soille, Morphological Image Analysis, Springer-Verlag, 1999.

    Google Scholar 

  11. T. Walter and J.-C. Klein, “Segmentation of color fundus images of the human retina: Detection of the optic disc and the vascular tree using morphological techniques,” proc. of ISMDA 2001, pp. 282–287, Oct 2001.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Walter, T., Klein, JC. (2002). Automatic Detection of Microaneurysms in Color Fundus Images of the Human Retina by Means of the Bounding Box Closing. In: Colosimo, A., Sirabella, P., Giuliani, A. (eds) Medical Data Analysis. ISMDA 2002. Lecture Notes in Computer Science, vol 2526. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-36104-9_23

Download citation

  • DOI: https://doi.org/10.1007/3-540-36104-9_23

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00044-0

  • Online ISBN: 978-3-540-36104-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics