Metronidazole, topical

doi:10.1007/3-540-29668-9_1772

Part of the book series: A to Z Essentials ((ATOZ))

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Trade name(s)

MetroGel; MetroCream; MetroLotion; Noritate

Generic available

Yes

Drug class

Nitroimidazole antibiotic

Mechanism of action

DNA disruption and inhibition of nucleic acid synthesis (may not be mechanism in skin disease treatment)

Dosage form

0.75% cream, gel; 1% cream

Dermatologic indications and dosage

See table

Metronidazole, topical. Dermatologic indications and dosage

Disease	Adult dosage	Child dosage
Rosacea	Apply once daily	Apply once daily

Common side effects

Cutaneous: burning sensation, erythema, skin eruption

Serious side effects

None

Drug interactions

None

Contraindications/precautions

Hypersensitivity to drug class or component

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References

Cohen AF, Tiemstra JD (2002) Diagnosis and treatment of rosacea. Journal of the American Board of Family Practice 15(3):214–217
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Editor information

Editors and Affiliations

Section of Dermatology, University of Arizona, P.O. Box 5038, 85724, Tucson, AZ, USA
N. Levine Prof. Dr.
University of Phoenix, 5099 East Grand Road, 85712, Tucson, AZ, USA
C. C. Levine

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(2004). Metronidazole, topical. In: Levine, N., Levine, C.C. (eds) Dermatology Therapy. A to Z Essentials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-29668-9_1772

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DOI: https://doi.org/10.1007/3-540-29668-9_1772
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-00864-4
Online ISBN: 978-3-540-29668-3
eBook Packages: Springer Book Archive

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