This is a preview of subscription content, log in via an institution.
Preview
Unable to display preview. Download preview PDF.
Références
Slamon DJ, Leyland-Jones B, Shak S et al. (2001) Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344: 783–92
Crone S, Zhao Y-Y, Fan L et al. (2002) Erb2 is essential in the prevention of dilated cardiomyopathy. Nature Medicine 5: 459–65
Seidman A, Hudis C, Pierri MK et al. (2002) Cardiac dysfunction in the trastuzumab clinical trials experience. J Clin Oncol 20: 1215–21
Perez EA, Rodeheffer R (2004) Clinical cardiac tolerability of trastuzumab. J Clin Oncol 22: 322–9
Sledge Gw, O’Neill A, Thor AD et al. (2001) Pilot trial of paclitaxel-Herceptin adjuvant therapy for early stage breast cancer (E2198). San Antonio Breast Cancer Symposium, Abst 4, 10–13 décembre
Carey A, Dees E, Sawyer L et al. (2002) Cardiotoxicity of trastuzumab given with weekly taxol immediately following 4AC as initial therapy for primary breast cancer American Society Clinical Oncology, Abst 253, 15–22 mai
Bianchi G, Albanell J, Eiermann W et al. (2003) Pilot trial of trastuzumab starting with or after the doxorubicin component of a doxorubicin plus paclitaxel regimen for women with HER2-positive advanced breast cancer. Clin Cancer Res 9: 5944–51
Trigo J, Climent M, Gil M et al. (2002) Cardiac safety and efficacy from a phase I trial of the liposomal doxorubicin TLC D-99 in combination with trastuzumab and paclitaxel in patients with HER2 positive locally advanced or metastatic breast cancer. Ann. Oncol 13: 51 (abst 183P)
Maria Theodoulou, Susana M Campos, Gerald Batist et al. (2002) TLC D99 (D, Myocet) and Herceptin (H) is safe in advanced breast cancer (ABC): final cardiac safety and efficacy analysis. American Society Clinical Oncology, Abst 216, 15–22 mai
Untch M, Eidtmann H, du Bois A et al. (2004) Cardiac safety of trastuzumab in combination with epirubicin and cyclophosphamide in women with metastatic breast cancer: results of a phase I trial. Eur J Cancer 40: 988–97
Carney WP, Neumann R, Lipton A et al. (2004) Monitoring the circulating levels of the HER2/neu oncoprotein in breast cancer. Clin Breast Cancer 5: 105–16
Molina R, Jo J, Filella X et al. (1999) C-erbB-2, CEA and CA 15.3 serum levels in the early diagnosis of recurrence of breast cancer patients Anticancer Res 19: 2551–5
Classen S, Kopp R, Possinger K et al. (2002) Clinical relevance of soluble c-erbB-2 for patients with metastatic breast cancer predicting the response to second-line hormone or chemotherapy. Tumour Biol 23: 70–5
Colomer R, Montero S, Lluch A et al. (2000) Circulating HER2 extracellular domain and resistance to chemotherapy in advanced breast cancer. Clin Cancer Res 6: 2356–62
Meng S, Tripathy D, Shete S et al. (2004) HER-2 gene amplification can be acquired as breast cancer progresses. PNAS; 101: 9393–8
Gancberg D, Di Leo A, Cardoso F et al. (2002) Comparison of HER-2 status between primary breast cancer and corresponding distant metastatic sites. Ann Oncol 13: 1036–43
Ellis MJ, Coop A, Singh B et al. (2001) Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1-and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a phase III randomized trial. J Clin Oncol 19: 3808–16
Colomer R, Llombart A, Ramos M et al. (2001) Serum HER-2 ECD and the efficacy of letrozole in ER+/PR+ metastatic breast cancer: preliminary results of a prospective study. San Antonio Breast Cancer Symposium, Abst 223: 10–13 décembre
Lipton A, Mouridsen H, Ali S (2001) Serum HER-2/neu and response to the aromatase inhibitor letrozole versus tamoxifen. San Antonio Breast Cancer Symposium, Abst. 6, 10–13 décembre
Colomer R, Montero S, Lluch A et al. (2000) Circulating HER2 extracellular domain and resistance to chemotherapy in advanced breast cancer. Clin Cancer Res 6: 2356–62
Muller V, Witzel I, Luck HJ et al. (2004) Prognostic and predictive impact of the HER-2/ neu extracellular domain (ECD) in the serum of patients treated with chemotherapy for metastatic breast cancer. Breast Cancer Res Treat, 86: 9–18
Luftner DI, Schaller G, Henschke P et al. (2002) Evaluation of serum HER-2/neu for outcome assessment and monitoring of Herceptin plus combination chemotherapy in metastatic breast cancer. San Antonio Breast Cancer Symposium, Abst 427, 11–14 décembre
Kostler WJ, Schwab B, Singer CF et al. (2004) Monitoring of serum Her-2/neu predicts response and progression-free survival to trastuzumab-based treatment in patients with metastatic breast cancer. Clin Cancer Res 10: 1618–24
Lotz JP, Brault D, Gligorov J et al. (2003) Serial monitoring of serum HER-2 extracellular domain (H-ECD) during trastuzumab-paclitaxel chemotherapy (CT) for metastatic breast cancer (MBC) pts: Preliminary results from the French experience (HER.ME.S protocol). American Society Clinical Oncology, Abst 208, 31 mai–03 juin
Leyland-Jones B, Gelmon K, Ayoub JP et al. (2003) Pharmacokinetics, safety, and efficacy of trastuzumab administered every three weeks in combination with paclitaxel. J Clin Oncol 21: 3965–7
Tripathy D, Slamon DJ, Cobleigh M et al. (2004) Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression. J Clin Oncol 22: 1063–70
Gelmon KA, Mackey J, Verma S et al. (2004) Use of trastuzumab beyond disease progression: observations from a retrospective review of case histories. Clin Breast Cancer 5: 52–8
Fountzilas G, Razis E, Tsavdaridis D et al. (2003) Continuation of trastuzumab beyond disease progression is feasible and safe in patients with metastatic breast cancer: a retrospective analysis of 80 cases by the hellenic cooperative oncology group. Clin Breast Cancer 4: 120–5
Gennari R, Menard S, Fagnoni F et al. (2004) Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumors overexpressing HER2. Clin Cancer Res 10: 5650–5
Van Pelt AE, Mohsin S, Elledge RM et al. (2003) Neoadjuvant trastuzumab and docetaxel in breast cancer: preliminary results. Clin Breast Cancer 4: 348–53
Wenzel C, Hussian D, Bartsch R et al. (2004) Preoperative therapy with epidoxorubicin and docetaxel plus trastuzumab in patients with primary breast cancer: a pilot study. J Cancer Res Clin Oncol 130: 400–4
Schneeweiss A, Kolay S, Aulmann S et al. (2004) Induction of remission in a patient with metastatic breast cancer refractory to trastuzumab and chemotherapy following treatment with gefitinib (Iressa, ZD 1839). Anticancer Drugs 15: 235–8
Moulder SL, Arteaga CL (2003) A Phase I/II Trial of trastuzumab and gefitinib in patients with Metastatic Breast Cancer that overexpresses HER2/neu (ErbB-2). Clin Breast Cancer 4: 142–5
Arteaga CL, O Neil A, Moulder SL et al. (2004) ECOG11000: a phase I-II study of combined blockade of the erbB receptor network with trastuzumab and gefitinib (‘Iressa’) in patients with HER-2overexpressing mestastatic breast cancer. San Antonio Breast Cancer Symposium, Abst 25: 8–11 décembre
Nahta R, Hung MC, Esteva FJ (2004) The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res 64: 2343–6
Arpino G, Weiss H, Wakeling AE et al. (2004) Complete disappearance of ER+/HER2+ breast cancer xenografts with the combination of gefitinib, trastuzumab and pertuzumab to block HER2 cross-talk with ER and restore Tamoxifen inhibition. San Antonio Breast Cancer Symposium, Abst 23: 8–11 decembre
Burris H, Hurwitz H, Dees C et al. (2003) A randomized multicenter, phase Ib study of the safety, biologis activity and clinical efficacy of the dual kinase inhibitor GW572018. San Antonio Breast Cancer Symposium, Abst 39: 3–6 décembre
Repp R, van Ojik HH, Valerius T et al. (2003) Phase I clinical trial of the bispecific antibody MDX-H210 (anti-FcgammaRI x anti-HER-2/neu) in combination with Filgrastim (G-CSF) for treatment of advanced breast cancer. Br J Cancer 89: 2234–43
Dang CT, D’Andrea GM, Moynahan ME et al. (2004) Phase II study of feasibility of dose-dense FEC followed by alternating weekly taxanes in high-risk, four or more node-positive breast cancer. Clin Cancer Res 10: 5754–61
Nagata Y, Lan KH, Zhou X et al. (2004) PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 6: 117–27
Pandolfi PP (2004) Breast cancer-loss of PTEN predicts resistance to treatment. N Engl J Med 351: 2337–8
Argiris A, Wang CX, Whalen SG et al. (2004) Synergistic interactions between tamoxifen and trastuzumab. Clin Cancer Res; 10: 1409–20
Ropero S, Menendez JA, Vazquez-Martin A et al. (2004) Trastuzumab plus tamoxifen: anti-proliferative and molecular interactions in breast carcinoma. Breast Cancer Res Treat 86: 125–37
Shou J, Massarweh S, Osborne K et al. (2004) Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer J Natl Cancer Inst 96: 926–35
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer-Verlag France, Paris
About this paper
Cite this paper
Roché, H. (2006). Cancers du sein avec HER2 surexprimé : quoi de neuf dans la prise en charge clinique ?. In: Cancer du sein. Springer, Paris. https://doi.org/10.1007/2-287-31109-2_12
Download citation
DOI: https://doi.org/10.1007/2-287-31109-2_12
Publisher Name: Springer, Paris
Print ISBN: 978-2-287-25174-0
Online ISBN: 978-2-287-31109-3