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Polysaccharides II pp 199–291Cite as

Functional Polymers Based on Dextran

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Part of the book series: Advances in Polymer Science ((POLYMER,volume 205))

Abstract

Dextran, comprising a family of neutral polysaccharides consisting of an α-(1 → 6) linked d-glucose main chain with varying proportions of linkages and branches, depending on the bacteria used, is an interesting starting material for chemical modification reactions for the design of new functional polymers with promising properties. The review summarises recent results on structure characterisation of dextran including some comments on biosynthesis of this important class of biopolymers. Applications of dextran are discussed as well. Chemical modification reactions of dextran are increasingly studied for the structure and hence property design. The review highlights recent progress in esterification of dextran, both inorganic and organic polysaccharide esters, etherification reactions towards ionic and non-ionic ethers, and the huge variety of different conversions mainly developed for the binding of drugs. It summarises recent developments in the application of dextran derivatives with a focus on the chemical structures behind these materials such as prodrugs, bioactivity of inorganic dextran esters, heparin sulfate mimics, hydrogels, nanoparticles and self assembly structures for surface modification.

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Authors and Affiliations

  1. Kompetenzzentrum Polysaccharidforschung, Friedrich-Schiller-Universität Jena, Humboldtstraße 10, 07743, Jena, Germany

    Thomas Heinze, Tim Liebert, Brigitte Heublein & Stephanie Hornig

Authors
  1. Thomas Heinze
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  2. Tim Liebert
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  3. Brigitte Heublein
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  4. Stephanie Hornig
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Correspondence to Thomas Heinze .

Editor information

Dieter Klemm

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© 2006 Springer-Verlag Berlin Heidelberg

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Heinze, T., Liebert, T., Heublein, B., Hornig, S. (2006). Functional Polymers Based on Dextran. In: Klemm, D. (eds) Polysaccharides II. Advances in Polymer Science, vol 205. Springer, Berlin, Heidelberg . https://doi.org/10.1007/12_100

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