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Glucose Sensing pp 283–310Cite as

Optically-Based Affinity Biosensors for Glucose

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Part of the book series: Topics in Fluorescence Spectroscopy ((TIFS,volume 11))

Abstract

The first biosensor was developed by Leland Clark who enhanced his oxygen electrode technology (Clark and Lyons, 1962) by interposing another membrane bound region between the detector and the sample that contained an enzyme (glucose oxidase) to produce the first “biosensor” for glucose. This paradigm has been followed for most of the biosensor developments to date. Leland Clark has been recently recognized for his breakthrough technology by receiving the Russ Prize from the National Academy of Engineering in 2005. A brief review of the early research on biosensors was provided by Schultz (1991).

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Author information

Authors and Affiliations

  1. University of California Riverside, CA, 92521, USA

    Jerome S. Schultz (Distinguished Professor)

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  1. Jerome S. Schultz
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Editor information

Editors and Affiliations

  1. The Institute of Fluorescence Medical Biotechnology Center, University of Maryland Biotechnology Institute, Baltimore, Maryland

    Chris D. Geddes

  2. Center for Fluorescence Spectroscopy and Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland

    Joseph R. Lakowicz

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Schultz, J.S. (2006). Optically-Based Affinity Biosensors for Glucose. In: Geddes, C.D., Lakowicz, J.R. (eds) Glucose Sensing. Topics in Fluorescence Spectroscopy, vol 11. Springer, Boston, MA. https://doi.org/10.1007/0-387-33015-1_11

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