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Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention pp 121–141Cite as

Cancer and Cancer Metastasis-Related Genes

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Part of the book series: Cancer Metastasis — Biology and Treatment ((CMBT,volume 1))

Abstract

Neoplastic disease follows the acquisition of mutations within genes, a process that may span many years. When these mutations occur in proto-oncogenes that normally encode for proteins which control the cell cycle, DNA repair and transcriptional events, the result is deregulation of cellular proliferation and other intracellular pathways, ultimately leading to tumour development.

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Hiscox, S. (2000). Cancer and Cancer Metastasis-Related Genes. In: Jiang, W.G., Mansel, R.E. (eds) Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention. Cancer Metastasis — Biology and Treatment, vol 1. Springer, Dordrecht. https://doi.org/10.1007/0-306-48388-2_5

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  • DOI: https://doi.org/10.1007/0-306-48388-2_5

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