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Mitochondrial Dysfunction in Chronic Fatigue Syndrome

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Mitochondria in Pathogenesis

Conclusions

Understanding of mitochondrial dysfunction in CFS will clearly benefit from more study. Our findings warrant detailed studies on larger patient and control populations. The siting of mitochondrial impairment may lead to approaches for alleviating some of the symptoms of CFS. Studies on the effects of cytokines on cellular and mitochondrial bioenergetics are important to see whether cytokines or similar molecules are involved in linking CFS immune disturbances to mitochondrial dysfunction, and to better understand the consequences of cytokine therapies for cancer and viral infection.

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Chazotte, B. (2002). Mitochondrial Dysfunction in Chronic Fatigue Syndrome. In: Lemasters, J.J., Nieminen, AL. (eds) Mitochondria in Pathogenesis. Springer, Boston, MA. https://doi.org/10.1007/0-306-46835-2_21

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