Biochemical and Biophysical Research Communications
Regular ArticleMarked Induction of the IAP Family Antiapoptotic Proteins Survivin and XIAP by VEGF in Vascular Endothelial Cells
References (33)
- et al.
Cell
(1996) - et al.
Curr. Biol.
(1993) - et al.
Cell
(1999) - et al.
J. Biol. Chem.
(1998) - et al.
Exp. Cell Res
(1999) - et al.
J. Biol. Chem.
(1998) Trends Cell Biol.
(1999)- et al.
Blood
(1999) - et al.
J. Biol. Chem.
(1998) - et al.
FASEB J.
(1999)
J. Clin. Invest.
Nature Med.
Proc. Natl. Acad. Sci. USA
Am. J. Pathol.
Nature
Oncogene
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