Research Articles“Crushing-Strength” of Compressed Tablets I: Comparison of Testers
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Emerging technologies for the non-invasive characterization of physical-mechanical properties of tablets
2017, International Journal of PharmaceuticsCitation Excerpt :The test involves subjecting the tablets to a uniform tumbling motion in a drum (friabilator) for a specified period/number of rotations, and measuring the percent weight loss. The externally applied force, which results in the breaking of a tablet in a specific plane is commonly used to analyze the mechanical integrity of tablets (Brook and Marshall, 1968). The USP Chapter on tablet breaking force provides guidelines to analyze the breaking force of tablets.
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