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Simple aspiration versus intercostal tube drainage for primary spontaneous pneumothorax in adults

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Abstract

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Background

In the management of primary spontaneous pneumothorax, simple aspiration is technically easier to perform. A systematic review may better define the clinical effectiveness and safety of simple aspiration compared to intercostal tube drainage in the management of primary spontaneous pneumothorax.

Objectives

To compare the clinically efficacy and safety of simple aspiration and intercostal tube drainage in the management of primary spontaneous pneumothorax.

Search methods

We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, Issue 2, 2006), MEDLINE (1966 to August 2006), and EMBASE (1980 to August 2006). We searched Current Controlled Trials metaRegister of Clinical Trials (compiled by Current Science) (August 2006). We checked the reference lists of trials and contacted trial authors . We imposed no language restriction.

Selection criteria

Randomized controlled trials comparing simple aspiration with intercostal tube drainage in adults aged 18 and over with primary spontaneous pneumothorax.

Data collection and analysis

Two authors independently assessed trial quality and extracted data. No statistical methods were necessary because only one study met the inclusion criteria.

Main results

Of the 1239 publications obtained from the search strategy, we examined six studies. Five studies were excluded, and one study of 60 participants was eligible for inclusion. There was no difference in immediate success rate of simple aspiration when compared with intercostal tube drainage in the management of primary spontaneous pneumothorax (relative risk (RR) = 0.93; 95% confidence interval (CI) 0.62 to 1.40). There was no significant difference in the early failure rate between the two interventions: RR 1.12 (95% CI 0.59 to 2.13). Simple aspiration reduced the proportion of patients hospitalized (RR = 0.52; 95% CI 0.36 to 0.75). There was no significant difference between the two interventions with regard to the following outcome measures: duration of hospitalization (weighted mean difference = 1.09; 95% CI 2.18 to 0.00); number of participants undergoing any procedure for lung pleurodesis within one year (RR = 0.95; 95% CI 0.41 to 2.22);and one year success rate (RR = 1.02; 95% CI 0.75 to 1.38).

Authors' conclusions

There is no significant difference between simple aspiration and intercostal tube drainage with regard to: immediate success rate, early failure rate, duration of hospitalisation, one year success rate and number of patients requiring pleurodesis at one year. Simple aspiration is associated with a reduction in the per cent of patients hospitalized when compared with intercostal tube drainage.

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.

Plain language summary

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Simple aspiration versus leaving a drainage tube in (intercostal tube drainage) for primary spontaneous pneumothorax in adults without obvious underlying lung disease

When air collects between the lung and the chest wall (the pleural space) this is described as a pneumothorax. This may be caused by trauma or lung disease, but sometimes it happens spontaneously without any obvious cause. When this happens the lungs cannot expand properly, which makes it difficult to breathe effectively. The person becomes breathless and has chest pain. It is important to treat the pneumothorax by removing the collection of air and allowing healing of the pleura, a thin membrane that covers the lungs to make a lining for them in the chest. For initial management where medical intervention is needed, the air can be removed either by simple aspiration, drawing the air out through a thin tube, or by insertion of a much larger chest tube in the space between the ribs (intercostal tube drainage). Both are done using local anaesthesia. Simple aspiration is technically easier to do. The review authors searched the medical literature and identified one randomized controlled study eligible for inclusion. The included study comprised a total of 60 patients with primary spontaneous pneumothorax; 27 of these underwent simple aspiration and 33 underwent intercostal tube drainage. The review found that simple aspiration is immediately as effective as intercostal tube drainage for primary spontaneous pneumothorax. However, simple aspiration is associated with less likelihood of being hospitalized. There was no significant difference between the two treatments with regard to the following: duration of hospitalization, early failure rate and one year success rate. The inclusion of only one small study in this review may have led to important differences between these two treatments being undetected.